4-(3,4-Difluoro-benzenesulfonylamino)-benzoic acid CAS 327072-97-9
| CAS No. | 327072-97-9 |
| Molecular Formula | C13H9F2NO4S |
| Molecular Weight | 313.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(3,4-Difluoro-benzenesulfonylamino)-benzoic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(3,4-Difluoro-benzenesulfonylamino)-benzoic acid (CAS 327072-97-9), a certified reference material (molecular formula C13H9F2NO4S, MW 313.28 g/mol) for analytical method development and quality control.
The molecular framework of 4-(3,4-Difluoro-benzenesulfonylamino)-benzoic acid (C13H9F2NO4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(3,4-Difluoro-benzenesulfonylamino)-benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H9F2NO4S |
| Molecular Weight | 313.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- 2-(2,4-Difluoro-benzenesulfonylamino)-benzoic acid (CAS 327103-13-9)
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- 4,6-Difluoro-N-(3-morpholinopropyl)benzo[d]thiazol-2-amine (CAS 1105188-72-4)
- Methyl 3,4-difluoro-2-iodophenylcarbamate (CAS 1356110-17-2)
- 5,7-Difluoro-2-phenylquinolin-4-ol (CAS 220598-55-0)
- 4-(2,3-Difluoro-5-methyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester (CAS 1704067-24-2)
- 2,3-Difluoro-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone (CAS 898786-80-6)
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Recommended Standards
- 4-((3-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazol-5-yl)methyl)morpholine (CAS 860784-33-4)
- 4-(4-Methoxyphenoxy)-N,N-dimethyl-6-(trifluoromethyl)pyrimidin-2-amine (CAS 338792-44-2)
- 4-((2,6-Difluorophenyl)sulfonamido)benzoic acid (CAS 885269-13-6)
- 4-Fluoro-3-[(6-methyl-imidazo[1,2-a]pyridine-3-carbonyl)-amino]-benzoic acid (CAS 2088945-60-0)
- 2-oxabicyclo[2.1.1]hexan-4-ylmethanamine;hydrochloride (CAS 2287280-60-6)
- N-((5-((2-Oxo-2-(thiazol-2-ylamino)ethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)benzamide (CAS 872613-57-5)
- 1-(2,3-Dimethoxy-6-nitrophenyl)ethanone (CAS 98300-40-4)
- 3,3-Dimethyl-1-(1,3-thiazol-2-yl)azetidin-2-one (CAS 303985-89-9)
- n-(2-Aminoethyl)-1h-1,2,4-triazole-3-carboxamide (CAS 817172-34-2)
- N-(tert-Butyl)nicotinamide (CAS 15828-08-7)
- 2-Amino-1,4-dicyclohexyl-4-phenyl-1H-imidazol-5(4H)-one (CAS 922498-21-3)
- Ethyl 2-[(4-nitrobenzene)sulfonamido]acetate (CAS 99069-33-7)
- (S)-2-(5-Chloro-2-methoxyphenyl)piperidine (CAS 1213089-18-9)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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