2-(4'-Fluoro-[1,1'-biphenyl]-3-yl)aceticacid CAS 327107-49-3

Purity 97%+In StockPharmaceutical Standards
CAS No.327107-49-3
Molecular FormulaC14H11FO2
Molecular Weight230.23 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4'-Fluoro-[1,1'-biphenyl]-3-yl)aceticacid CAS 327107-49-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 230.23 g/mol gives 2-(4'-Fluoro-[1,1'-biphenyl]-3-yl)aceticacid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(4'-Fluoro-[1,1'-biphenyl]-3-yl)aceticacid (CAS 327107-49-3), molecular formula C14H11FO2 and molecular weight 230.23 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(4'-Fluoro-[1,1'-biphenyl]-3-yl)aceticacid (C14H11FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H11FO2
Molecular Weight230.23 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing

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