3-Amino-N-(2-fluorophenyl)benzene-1-sulfonamide CAS 328028-26-8
| CAS No. | 328028-26-8 |
| Molecular Formula | C12H11FN2O2S |
| Molecular Weight | 266.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Amino-N-(2-fluorophenyl)benzene-1-sulfonamide (CAS 328028-26-8), molecular formula C12H11FN2O2S and molecular weight 266.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Amino-N-(2-fluorophenyl)benzene-1-sulfonamide (C12H11FN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-N-(2-fluorophenyl)benzene-1-sulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H11FN2O2S |
| Molecular Weight | 266.29 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- Ethyl 5-(((4-fluorophenyl)thio)methyl)isoxazole-3-carboxylate (CAS 823219-96-1)
- 4-Isopropyl-2-pyridinecarboxylic Acid (CAS 83282-36-4)
- tert-butyl 4-amino-3-cyclopropylbutanoate (CAS 1989671-95-5)
- 3,3-Dimethoxytetrahydro-4H-pyran-4-one (CAS 1785762-24-4)
- 2-(2,3-Difluorophenyl)ethanol (CAS 126163-30-2)
- Biotinyl-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 213779-13-6)
Why CATO?
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