2,5-diamino-N-(2-chlorophenyl)benzenesulfonamide CAS 328028-33-7
| CAS No. | 328028-33-7 |
| Molecular Formula | C12H12ClN3O2S |
| Molecular Weight | 297.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.76 g/mol gives 2,5-diamino-N-(2-chlorophenyl)benzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,5-diamino-N-(2-chlorophenyl)benzenesulfonamide (CAS 328028-33-7), molecular formula C12H12ClN3O2S and molecular weight 297.76 g/mol, is a CATO reference standard with documented purity and traceability.
2,5-diamino-N-(2-chlorophenyl)benzenesulfonamide (C12H12ClN3O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12ClN3O2S |
| Molecular Weight | 297.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related diamino Standards
- 3,4-Diamino-N-(2-chlorophenyl)benzenesulfonamide (CAS 326023-07-8)
- 3,4-Diamino-N-(4-chlorophenyl)benzenesulfonamide (CAS 380342-96-1)
- 4-(3,6-diamino-9H-carbazol-9-yl)-4-oxobutanoic acid (CAS CATO-C3D-262425)
- 1,6-Diamino-4-(4-hydroxy-3-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile (CAS 354989-31-4)
- 1,2-Diamino-N-(sec-butyl)-1H-pyrrolo[2,3-b]quinoxaline-3-carboxamide (CAS 881551-42-4)
- 1,8-Diamino-6-methoxy-3-piperidin-1-yl-2,7-naphthyridine-4-carbonitrile (CAS 380570-19-4)
- 2,6-Diamino-4-(4-isopropylphenyl)-4H-thiopyran-3,5-dicarbonitrile (CAS 303066-28-6)
- 4,6-Diamino-2-((o-tolyloxy)methyl)-2,3-dihydrofuro[2,3-b]pyridine-5-carbonitrile (CAS 343374-98-1)
Recommended Standards
- 4-(3-Chlorophenyl)-5-(ethylsulfonyl)pyrimidin-2-amine (CAS 1707605-71-7)
- 2-Chloro-7-methyl-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde (CAS 955979-02-9)
- 4-(4-Chlorophenyl)-5-(ethylsulfonyl)pyrimidin-2-amine (CAS 1707568-22-6)
- 3-((4-Chlorophenyl)sulfonyl)-4,6-dimethylpyridin-2(1H)-one (CAS 321431-06-5)
- 2-Methylfuran-3-sulfonyl chloride (CAS 60965-56-2)
- 6-Butoxy-9H-purin-2-amine (CAS 8045-27-0)
- 1-(4-Methoxyphenyl)-1H-1,2,4-triazole-3-carbaldehyde (CAS 917910-97-5)
- 3(2H)-furanone, dihydro-4-(HydroxymethylenE)-2,2-dimethyl- (CAS 142996-71-2)
- Methyl 3-iodo-4-morpholinobenzoate (CAS 1131614-73-7)
- Dapoxetine Impurity 94 (CAS CATO-C4X-143994)
- 2-(2,3-Dihydro-1-benzofuran-7-yl)acetic acid (CAS 152149-94-5)
- 5-(3-Fluorophenoxy)-2,2-dimethylpentan-1-amine (CAS 1267645-13-5)
- 2-Ethyl-6-(1H-pyrrol-1-yl)-1,3-benzoxazole (CAS 861206-65-7)
- Semaglutide impurity 45 (CAS CATO-C4X-222645)
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