1-(2-Chloro-4-fluorobenzyl)piperidin-4-amine dihydrochloride CAS 328083-90-5

Purity 97%+In StockPharmaceutical Standards
CAS No.328083-90-5
Molecular FormulaC17H24F2N2O2
Molecular Weight326.38 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2-Chloro-4-fluorobenzyl)piperidin-4-amine dihydrochloride CAS 328083-90-5 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO supplies 1-(2-Chloro-4-fluorobenzyl)piperidin-4-amine dihydrochloride (CAS 328083-90-5), a certified reference material (molecular formula C17H24F2N2O2, MW 326.38 g/mol) for analytical method development and quality control.

1-(2-Chloro-4-fluorobenzyl)piperidin-4-amine dihydrochloride (C17H24F2N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), 1-(2-Chloro-4-fluorobenzyl)piperidin-4-amine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC17H24F2N2O2
Molecular Weight326.38 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

Related Chloro Standards

Recommended Standards

Why CATO?