8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one CAS 328277-09-4
| CAS No. | 328277-09-4 |
| Molecular Formula | C10H5ClN2O2 |
| Molecular Weight | 220.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 220.61 g/mol gives 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one (CAS 328277-09-4), molecular formula C10H5ClN2O2 and molecular weight 220.61 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one (C10H5ClN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-Chloro[1]benzofuro[3,2-d]pyrimidin-4(3H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H5ClN2O2 |
| Molecular Weight | 220.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-Chloro-6,7-dihydroxyquinoline-3-carbonitrile (CAS 1415562-51-4)
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Recommended Standards
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- (R)-4-(2-Aminopropyl)tetrahydro-2H-pyran-4-ol (CAS 2765213-34-9)
- 6-(Bromomethyl)-1-naphthonitrile (CAS 81940-37-6)
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