Lisinopril EP Impurity C CAS 328385-86-0
| CAS No. | 328385-86-0 |
| Molecular Formula | C21H29N3O4 |
| Molecular Weight | 387.47 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lisinopril EP Impurity C.
As a process- or degradation-related impurity, Lisinopril EP Impurity C (CAS 328385-86-0, C21H29N3O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Lisinopril EP Impurity C (C21H29N3O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lisinopril EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H29N3O4 |
| Molecular Weight | 387.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
Related Lisinopril Standards
- Lisinopril (8R,S)-Diketopiperazine (Mixture of Diastereomers) (CAS 1092813-99-4)
- Lisinopril EP Impurity D (CAS 219677-82-4)
- Lisinopril (CAS 76547-98-3)
- Lisinopril EP Impurity E (CAS 85955-59-5)
- Lisinopril-D5 (CAS 1356905-39-9)
- Lisinopril EP Impurity F (CAS 1132650-67-9)
- Lisinopril Impurity 15 (CAS 116169-90-5)
- Lisinopril Impurity 11 (CAS CATO-C4X-168111)
Recommended Standards
- Mivacurium Chloride Impurity 21 (CAS 104758-47-6)
- Tert-butyl 4-(4-(1,3-dioxoisoindolin-2-yl)butyl)piperazine-1-carboxylate (CAS 745048-06-0)
- Atracurium Impurity 118 (CAS 24734-71-2)
- tert-Butyl (R)-(3-(3-(3,4-dimethoxyphenyl)-1-hydroxypropyl)phenyl)carbamate (CAS 215168-76-6)
- Tranexamic Impurity 16 (CAS 1642-81-5)
- Malic Acid Impurity 4 (CAS 56235-92-8)
- Epinephrine Impurity 62 Formate Salt (CAS 2947-02-6(free base）)
- 2,5-Dibromo-3,6-difluorobenzamide (CAS 1803713-73-6)
- Sildenafil Impurity 305 (CAS CATO-C4X-1128305)
- 1-(2-Cyclopropylphenyl)ethan-1-one (CAS 485402-63-9)
- 2-(Difluoromethyl)-3-iodo-4-(trifluoromethyl)pyridine-6-acetonitrile (CAS 1805198-32-6)
- 1,1-Dimethylhydrazine (CAS 57-14-7)
- (4-Isopropylphenyl)(2-methylpyridin-4-yl)methanone (CAS 1187171-25-0)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com