5-(2-Chlorobenzyl)-2-hydroxybenzaldehyde CAS 328565-20-4
| CAS No. | 328565-20-4 |
| Molecular Formula | C14H11ClO2 |
| Molecular Weight | 246.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-(2-Chlorobenzyl)-2-hydroxybenzaldehyde (CAS 328565-20-4), a certified reference material (molecular formula C14H11ClO2, MW 246.69 g/mol) for analytical method development and quality control.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system, 5-(2-Chlorobenzyl)-2-hydroxybenzaldehyde is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 246.69 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H11ClO2 |
| Molecular Weight | 246.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chlorobenzyl Standards
- 3-[(2-Chlorobenzyl)oxy]benzaldehyde (CAS 168084-94-4)
- 3-[(3-Chlorobenzyl)oxy]benzaldehyde (CAS 168084-95-5)
- 2-((3-Chlorobenzyl)oxy)benzaldehyde (CAS 40359-59-9)
- 2-[(2-Chlorobenzyl)oxy]benzaldehyde (CAS 53389-99-4)
- 2-[(4-Chlorobenzyl)oxy]benzaldehyde (CAS 52803-59-5)
- 3-((4-Chlorobenzyl)oxy)benzaldehyde (CAS 24550-39-8)
- 3-Chlorobenzyl benzoate (CAS 63987-52-0)
- 4-((3-Chlorobenzyl)oxy)benzaldehyde (CAS 59067-43-5)
Recommended Standards
- 4-CHloro-benzoic acid benzyl ester (CAS 67483-73-2)
- 5-Chloro-2-hydroxy-4-methylbenzophenone (CAS 68751-90-6)
- 4-Amino-N-(4-chlorophenyl)benzamide (CAS 955-97-5)
- 6-Chloro-4-(2-methylphenyl)-3-pyridinecarboxamide (CAS 342417-00-9)
- Diethyl 1H-indole-2,5-dicarboxylate (CAS 127221-02-7)
- N1-(Pyridin-4-yl)ethane-1,2-diamine (CAS 64281-29-4)
- N-(3,4-Difluoro-benzyl)-o-methyl-hydroxylamine (CAS 543730-86-5)
- 3′-(1-Pyrrolidinylcarbonyl)[1,1′-biphenyl]-3-acetic acid (CAS 1375069-22-9)
- 1-(4-Fluorobenzyl)-1H-indole-3-carboxylic Acid (CAS 226883-79-0)
- 3-(((5-Methylthiophen-2-yl)methyl)amino)thietane 1,1-dioxide (CAS 1879200-77-7)
- Methyl 2-(2-oxoindolin-5-yl)acetate (CAS 109737-05-5)
- (1R,2S,3R,5S)-3-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-5-methylcyclopentane-1,2-diol (CAS 106175-19-3)
- 9-(2-Pyridyl)carbazole (CAS 23866-67-3)
- Peptide Impurity 27 (CAS 1350456-68-6)
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