328947-93-9 RI376RM5MT LGD-2226 UNII-RI376RM5MT 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one CAS 328947-93-9
| CAS No. | 328947-93-9 |
| Molecular Formula | C14H15F9N2O |
| Molecular Weight | 398.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 328947-93-9 RI376RM5MT LGD-2226 UNII-RI376RM5MT 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one (CAS 328947-93-9), a certified reference material (molecular formula C14H15F9N2O, MW 398.27 g/mol) for analytical method development and quality control.
The molecular framework of 328947-93-9 RI376RM5MT LGD-2226 UNII-RI376RM5MT 6-(Bis-(2,2,2-trifluoroethyl)amino)-4-trifluoromethyl-1H-quinolin-2-one (C14H15F9N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H15F9N2O |
| Molecular Weight | 398.27 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl 4-((2-bromo-4-fluorophenyl)amino)-4-cyanopiperidine-1-carboxylate (CAS 2204141-39-7)
- 2-Methyl-1-(phenylsulfonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine (CAS 1014613-31-0)
- N-(4-Bromobenzyl)-N-tosylglycine (CAS 593261-60-0)
- 1-[4-(4-Bromophenyl)-1,3-thiazol-2-yl]-3-phenyl-1H-pyrazol-5-ol (CAS 1020052-17-8)
- 1-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azepan-4-yl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 2137578-44-8)
- 4-Bromo-3-(difluoromethyl)-5-iodopicolinaldehyde (CAS 1805374-93-9)
- 3-((3-Chloro-4-methylphenyl)amino)-1-(p-tolyl)propan-1-one (CAS 477334-05-7)
- 1-(3-(Difluoromethoxy)phenyl)-3-(1,5-dimethyl-1H-pyrazol-4-yl)prop-2-en-1-one (CAS 1005647-45-9)
- N-(2-Cyclopropoxy-6-(methylamino)phenyl)methanesulfonamide (CAS 1243313-34-9)
- 5-Chloro-3-methylimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1268520-94-0)
- Efavirenz USP Related Compound A (CAS 209414-27-7；154598-58-0)
- 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid (CAS 1782902-92-4)
- 3-(3,4-Dichlorophenyl)-3-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid (CAS 478260-04-7)
- D-Asp15-Tirzepatide (CAS CATO-CPTD788919)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com