6-Amino-4-(difluoromethyl)quinolin-2(1H)-one CAS 328955-81-3

Purity 97%+In StockPharmaceutical Standards
CAS No.328955-81-3
Molecular FormulaC10H8F2N2O
Molecular Weight210.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

6-Amino-4-(difluoromethyl)quinolin-2(1H)-one CAS 328955-81-3 chemical structure

Description

The occurrence of 6-Amino-4-(difluoromethyl)quinolin-2(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

6-Amino-4-(difluoromethyl)quinolin-2(1H)-one (CAS 328955-81-3) is a high-purity analytical reference standard with the molecular formula C10H8F2N2O and a molecular weight of 210.18 g/mol.

Structurally, 6-Amino-4-(difluoromethyl)quinolin-2(1H)-one (C10H8F2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 210.18 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 6-Amino-4-(difluoromethyl)quinolin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC10H8F2N2O
Molecular Weight210.18 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

Related Amino Standards

Recommended Standards

Why CATO?