5-(2-Hydroxyethyl)-1-methylpyridin-2(1H)-one CAS 32897-20-4
| CAS No. | 32897-20-4 |
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 153.18 g/mol gives 5-(2-Hydroxyethyl)-1-methylpyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(2-Hydroxyethyl)-1-methylpyridin-2(1H)-one (CAS 32897-20-4), molecular formula C8H11NO2 and molecular weight 153.18 g/mol, is a CATO reference standard with documented purity and traceability.
5-(2-Hydroxyethyl)-1-methylpyridin-2(1H)-one (C8H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Hydroxyethyl Standards
- 4-((2-Hydroxyethyl)amino)phenol (CAS 49865-92-1)
- 2-hydroxyethyl-6-hydroxymethylpyridine (CAS CATO-C4X-183851)
- 5-(2-Hydroxyethyl)thiophene-2-carbonitrile (CAS 1333222-43-7)
- 5-(1-Hydroxyethyl)thiophene-2-carbonitrile (CAS 353282-69-6)
- n-(2-Hydroxyethyl)-N-methylmethanesulfonamide (CAS 87113-83-5)
- 4-(2-Hydroxyethyl)benzene-1,3-diol (CAS 101383-02-2)
- 2-(2-Hydroxyethyl)benzene-1,4-diol (CAS 13398-95-3)
- (r)-4-(1-Hydroxyethyl)benzene-1,3-diol (CAS 1821843-82-6)
Recommended Standards
- 5-(2-Aminoethyl)benzene-1,3-diol (CAS 29866-11-3)
- 5-(Aminomethyl)-2-ethylpyridazin-3(2H)-one (CAS 779353-74-1)
- 5-(1h-1,2,4-Triazol-1-yl)pentan-2-one (CAS 344326-20-1)
- 5-(Cyclopropylmethoxy)-1H-pyrazol-3-amine (CAS 852443-66-4)
- 4-Cyclopropyl-1H-pyrazol-3-amine (CAS 673475-74-6)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-3-(trifluoromethyl)benzamide (CAS 477866-74-3)
- 6-(4-Fluorophenyl)pyridazin-3-amine (CAS 105538-07-6)
- N-(2-(5-Propyl-2,5-dihydro-1,2,4-oxadiazol-3-yl)phenyl)benzamide (CAS 89143-39-5)
- (R)-4-(2-aminopropyl)phenol (CAS 1518-89-4)
- 1,5,8-Trihydroxy-2-(p-tolylamino)anthracene-9,10-dione (CAS 61548-23-0)
- 5-Propyl-1-(3-(trifluoromethyl)benzyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1338674-13-7)
- 4-Bromo-2-isopropylpyridine (CAS 908267-63-0)
- (5-(tert-Butyl)-2-methylphenyl)methanol (CAS 129716-13-8)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
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