2-Mercapto-4-(thiophen-2-yl)-6-(trifluoromethyl)nicotinonitrile CAS 329056-11-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Mercapto-4-(thiophen-2-yl)-6-(trifluoromethyl)nicotinonitrile.

2-Mercapto-4-(thiophen-2-yl)-6-(trifluoromethyl)nicotinonitrile (CAS 329056-11-3), molecular formula C11H5F3N2S2 and molecular weight 286.30 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, 2-Mercapto-4-(thiophen-2-yl)-6-(trifluoromethyl)nicotinonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 286.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Mercapto-4-(thiophen-2-yl)-6-(trifluoromethyl)nicotinonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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