2-((2-(3-Chloro-4-methylphenyl)-2-oxoethyl)thio)-3-phenylquinazolin-4(3H)-one CAS 329079-80-3
| CAS No. | 329079-80-3 |
| Molecular Formula | C23H17ClN2O2S |
| Molecular Weight | 420.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-((2-(3-Chloro-4-methylphenyl)-2-oxoethyl)thio)-3-phenylquinazolin-4(3H)-one (CAS 329079-80-3), a certified reference material (molecular formula C23H17ClN2O2S, MW 420.91 g/mol) for analytical method development and quality control.
2-((2-(3-Chloro-4-methylphenyl)-2-oxoethyl)thio)-3-phenylquinazolin-4(3H)-one (C23H17ClN2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 2-((2-(3-Chloro-4-methylphenyl)-2-oxoethyl)thio)-3-phenylquinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H17ClN2O2S |
| Molecular Weight | 420.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-5-(indoline-1-carbonyl)-N-((tetrahydrofuran-2-yl)methyl)benzenesulfonamide (CAS 930938-70-8)
- 6-Chloro-N-(3,3-diethoxypropyl)-4-(methylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxamide (CAS 866142-53-2)
- 2-Chloro-3-(4-(indoline-1-carbonyl)piperidin-1-yl)naphthalene-1,4-dione (CAS 685106-73-4)
- 6-Chloro-2-(((3,5-dimethylphenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 866049-02-7)
- N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]-1,1,2,2,3,3,3-heptadeuteriopropane-1-sulfonamide (CAS 1304096-50-1)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-[(phenylcarbamothioyl)amino]acetamide (CAS 1022600-30-1)
- 3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(3-methylbenzoyl)-1H-pyrazole (CAS 477711-71-0)
- 3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(4-methylbenzoyl)-1H-pyrazole (CAS 477711-69-6)
Recommended Standards
- 1-[(3-Chlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338419-06-0)
- 2-(4-Chlorophenyl)-3-((4-(2-fluorophenyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridine (CAS 338401-78-8)
- 1-[(2-Chlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-98-7)
- 1-(4-Chlorobenzyl)-3'-phenylspiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 338419-04-8)
- 5-(P-tolyl)thiazolo[2,3-c][1,2,4]triazole-3-thiol (CAS 500112-74-3)
- 1-Boc-4-[carboxy-(1H-indol-2-yl)-methyl]-piperazine (CAS 885275-32-1)
- [5-(2,2,2-trifluoroethyl)-1,2,4-oxadiazol-3-yl]methanamine hydrochloride (CAS 1421601-20-8)
- cis-4-Methoxy-2-methyl-piperidine hydrochloride (CAS 1621225-22-6)
- tert-Butyl 5-bromo-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate (CAS 1620575-03-2)
- Benfuracarb (CAS 82560-54-1)
- 2-Fluoro-4'-(trifluoromethyl)biphenyl-3-carboxylic acid (CAS 1261669-11-7)
- 2-[(methylsulfonyl)methyl]-1H-benzimidazole (CAS 24092-75-9)
- 2-(Benzyloxy)-4-methoxybenzoic acid (CAS 13618-49-0)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com