N-(4-bromo-3-methylphenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide CAS 329080-30-0
| CAS No. | 329080-30-0 |
| Molecular Formula | C23H18BrN3O2S |
| Molecular Weight | 480.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 480.38 g/mol gives N-(4-bromo-3-methylphenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-(4-bromo-3-methylphenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide (CAS 329080-30-0), a certified reference material (molecular formula C23H18BrN3O2S, MW 480.38 g/mol) for analytical method development and quality control.
The molecular framework of N-(4-bromo-3-methylphenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide (C23H18BrN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-bromo-3-methylphenyl)-2-((4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H18BrN3O2S |
| Molecular Weight | 480.38 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- 2-Bromo-N-((2-(2,3-dimethylphenyl)benzo[d]oxazol-5-yl)carbamothioyl)benzamide (CAS 590396-68-2)
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- 4-Bromo-3-oxo-1-trityl-2,3-dihydro-1H-indazole-5-carbonitrile (CAS 2756657-94-8)
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- 1-Bromo-8H-perfluorooctane (CAS 89740-38-5)
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- 4-Bromo-5-fluoro-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 2378746-99-5)
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Recommended Standards
- N-(3-Bromophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477318-70-0)
- 11-O-Galloylbergenin (CAS 82958-44-9)
- N-(2-Bromophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477318-72-2)
- Aripiprazole N,N-Dioxide (CAS 573691-13-1)
- 6-[(E)-2-(4-Methylphenyl)ethenyl]-4-[(Z)-2-(4-methylphenyl)ethenyl]-2-(propylsulfanyl)pyridine-3-carbonitrile (CAS 303985-28-6)
- 3-Methoxy-1,2,4-thiadiazol-5-amine (CAS 98022-43-6)
- 3-Ethyl-5-nitrobenzofuran (CAS 88521-68-0)
- 4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]Oct-2-ene-2-carboxylate (CAS 172673-09-5)
- Ioversol Impurity 36 (CAS 80462-96-0)
- (R)-2-(2,2,3-Trimethylcyclopent-3-en-1-yl)acetic acid (CAS 28973-89-9)
- 4-Bromophenol Acetate (CAS 1927-95-3)
- 5-Fluoro-2-methoxypyridine 1-oxide (CAS 51173-07-0)
- 1-{4-[(2E)-3-(4-Nitrophenyl)prop-2-enoyl]phenyl}-1H-pyrrole-2,5-dione (CAS 949923-56-2)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
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