5-(2-Chloro-5-nitrophenyl)furan-2-carbaldehyde CAS 329222-78-8
| CAS No. | 329222-78-8 |
| Molecular Formula | C11H6ClNO4 |
| Molecular Weight | 251.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(2-Chloro-5-nitrophenyl)furan-2-carbaldehyde (CAS 329222-78-8) is a high-purity analytical reference standard with the molecular formula C11H6ClNO4 and a molecular weight of 251.62 g/mol.
The molecular framework of 5-(2-Chloro-5-nitrophenyl)furan-2-carbaldehyde (C11H6ClNO4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-(2-Chloro-5-nitrophenyl)furan-2-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6ClNO4 |
| Molecular Weight | 251.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 5-(2-Chloro-4-nitrophenyl)furan-2-carbaldehyde (CAS 327049-94-5)
- 5-(4-Chloro-2-nitrophenyl)furan-2-carbaldehyde (CAS 480439-09-6)
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Recommended Standards
- 5-(2-Chloronicotinoyl)-2-furoic acid (CAS 914203-45-5)
- 5-(2-Nitrophenyl)furan-2-carbonyl chloride (CAS 61941-88-6)
- Benzonitrile, 5-(2-chloro-4-pyrimidinyl)-2,4-difluoro- (CAS 1956307-41-7)
- 5-(3-Nitrophenyl)furan-2-carbonyl chloride (CAS 61941-87-5)
- [3-(2,3-dihydro-1-benzofuran-5-yl)-4,5-dihydro-1,2-oxazol-5-yl]methanamine hydrochloride (CAS 1803561-63-8)
- 2,2,2-Trifluoro-1-(4-isobutylphenyl)ethan-1-one (CAS 118569-68-9)
- Ethyl 4-chloro-5-formyl-3-methylbenzofuran-2-carboxylate (CAS 137987-77-0)
- (S)-2-Amino-2,4-dimethylpentan-1-ol (CAS 1352447-28-9)
- 4’-Epi Lamivudine-15N2,13C (CAS 1246815-07-5)
- 2-Bromo-4-fluorobenzylamine hydrochloride, 97% (CAS 289038-14-8)
- 1-(2-methanesulfonylethyl)-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole (CAS 1339892-52-2)
- 3,4,5-Trifluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2657617-93-9)
- 4-Nitrobenzo[4,5]imidazo[1,2-a]pyridine (CAS 33452-78-7)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
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