2-(2,3,4-Trichlorophenyl)quinoline-4-carboxylic acid CAS 329265-48-7
| CAS No. | 329265-48-7 |
| Molecular Formula | C16H8Cl3NO2 |
| Molecular Weight | 352.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2,3,4-Trichlorophenyl)quinoline-4-carboxylic acid.
2-(2,3,4-Trichlorophenyl)quinoline-4-carboxylic acid (CAS 329265-48-7), molecular formula C16H8Cl3NO2 and molecular weight 352.60 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2,3,4-Trichlorophenyl)quinoline-4-carboxylic acid (C16H8Cl3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl3NO2 |
| Molecular Weight | 352.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Trichlorophenyl Standards
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- 2,4,6-Trichlorophenyl 2-fluorobenzenesulfonate (CAS 1171919-36-0)
- 2,4,6-Trichlorophenyl 4-fluorobenzenesulfonate (CAS 1171919-37-1)
- 2,4,6-Trichlorophenyl 1,2-dimethyl-1H-imidazole-4-sulfonate (CAS 1171919-44-0)
- 2-(3,4,5-Trichlorophenyl)-5-(trifluoromethyl)pyridine-3-methanol (CAS 1361600-20-5)
- 1-[(2,4,5-Trichlorophenyl)sulfonyl]-2-pyrrolidinecarboxylic acid (CAS 251097-12-8)
- 2-[(2,4,6-Trichlorophenyl)amino]-2,3,3a,4,7,7a-hexahydro-1H-isoindole-1,3-dione (CAS 350680-03-4)
Recommended Standards
- Methyl trans-13-Docosenoate (CAS 7439-44-3)
- 8-Chloro-2-(2,4-dichlorophenyl)quinoline-4-carboxylic acid (CAS 863180-69-2)
- Erucic Acid Methyl Ester (CAS 1120-34-9)
- 8-Chloro-2-(2,5-dichlorophenyl)quinoline-4-carboxylic acid (CAS 863180-70-5)
- 2-Propenoic acid, 2-methyl-, dodecyl ester, polymer with methyl 2-methyl-2-propenoate (CAS 30795-64-3)
- N-(2,6-Difluorobenzyl)-2-((3-oxo-2,3-dihydro-1H-inden-5-yl)oxy)acetamide (CAS 1203387-04-5)
- 1-(4-((3-(3-(Pyrazin-2-yl)-1,2,4-oxadiazol-5-yl)azetidin-1-yl)sulfonyl)phenyl)ethan-1-one (CAS 1324680-00-3)
- 1,3-Dithiolan-2-imine (CAS 4472-81-5)
- 2-Fluoro-4-(methylamino)benzonitrile (CAS 171049-40-4)
- 2,6-Diamino-4-(difluoromethyl)pyridin-3-ol (CAS 1803669-90-0)
- Methyl 3'-methyl-[1,1'-biphenyl]-3-carboxylate (CAS 128460-74-2)
- Methyl 5-methylimidazo[1,2-a]pyrimidine-7-carboxylate (CAS 916212-75-4)
- tert-Butyl 2-(cyclopentylamino)-2-oxoethylcarbamate (CAS 1824064-71-2)
- Semaglutide Impurity 13 (CAS CATO-C4X-222613)
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