2-{[4-(4-benzylpiperazino)-3-nitrophenyl]methylene}malononitrile CAS 329778-08-7
| CAS No. | 329778-08-7 |
| Molecular Formula | C21H19N5O2 |
| Molecular Weight | 373.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-{[4-(4-benzylpiperazino)-3-nitrophenyl]methylene}malononitrile (CAS 329778-08-7), molecular formula C21H19N5O2 and molecular weight 373.41 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-{[4-(4-benzylpiperazino)-3-nitrophenyl]methylene}malononitrile (C21H19N5O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-{[4-(4-benzylpiperazino)-3-nitrophenyl]methylene}malononitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H19N5O2 |
| Molecular Weight | 373.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
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Recommended Standards
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- 3-(3-Methoxyphenyl)-N-(naphthalen-1-yl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483993-58-4)
- ethyl 1-(2-amino-4-nitrophenyl)-4-piperidinecarboxylate (CAS 1221792-44-4)
- 1-(Iodomethyl)-3,5-dimethoxybenzene (CAS 66769-61-7)
- Methyl (2E)-3-{3-[(E)-[(dimethylamino)methylidene]amino]-4,6-dimethylthieno[2,3-b]pyridin-2-yl}prop-2-enoate (CAS 338956-44-8)
- ((2R,3R,4R,5R)-5-(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)-3-hydroxy-4-methoxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate (CAS 61556-44-3)
- tert-butyl (6S)-6-(aminomethyl)-1,4-oxazepane-4-carboxylate (CAS 2165339-00-2)
- Pentafluorophenyl pyridine-2-sulfonate (CAS 1199262-21-9)
- 1-(2-Amino-5-hydroxypyridin-4-yl)ethan-1-one (CAS 1393539-36-0)
- (1-Methyl-5-(trifluoromethyl)-1h-pyrazol-4-yl)methanamine (CAS 894779-69-2)
- 4-Cyclopentyl-2-(methylsulfonyl)pyrimidine-5-carboxylic acid (CAS 1956377-14-2)
- Insulin degludec (CAS 844439-96-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com