(2E)-3-(4-Chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide CAS 329778-18-9

Purity 97%+In StockPharmaceutical Standards
CAS No.329778-18-9
Molecular FormulaC19H17ClN2O
Molecular Weight324.80 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2E)-3-(4-Chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide CAS 329778-18-9 chemical structure

Description

The occurrence of (2E)-3-(4-Chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (2E)-3-(4-Chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide (CAS 329778-18-9), a certified reference material (molecular formula C19H17ClN2O, MW 324.80 g/mol) for analytical method development and quality control.

(2E)-3-(4-Chlorophenyl)-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide (C19H17ClN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC19H17ClN2O
Molecular Weight324.80 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms2

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