N-(4-bromo-2-fluorophenyl)-3-(4-chlorophenyl)acrylamide CAS 329778-48-5

Purity 97%+In StockPharmaceutical Standards
CAS No.329778-48-5
Molecular FormulaC15H10BrClFNO
Molecular Weight354.60 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-bromo-2-fluorophenyl)-3-(4-chlorophenyl)acrylamide CAS 329778-48-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-bromo-2-fluorophenyl)-3-(4-chlorophenyl)acrylamide.

N-(4-bromo-2-fluorophenyl)-3-(4-chlorophenyl)acrylamide (CAS 329778-48-5), molecular formula C15H10BrClFNO and molecular weight 354.60 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(4-bromo-2-fluorophenyl)-3-(4-chlorophenyl)acrylamide (C15H10BrClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), N-(4-bromo-2-fluorophenyl)-3-(4-chlorophenyl)acrylamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC15H10BrClFNO
Molecular Weight354.60 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms1

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