N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(3-chlorophenyl)piperazin-1-yl)acetamide CAS 329779-26-2
| CAS No. | 329779-26-2 |
| Molecular Formula | C19H18Cl2F3N3O |
| Molecular Weight | 432.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(3-chlorophenyl)piperazin-1-yl)acetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(3-chlorophenyl)piperazin-1-yl)acetamide (CAS 329779-26-2), molecular formula C19H18Cl2F3N3O and molecular weight 432.27 g/mol, is a CATO reference standard with documented purity and traceability.
N-(2-chloro-5-(trifluoromethyl)phenyl)-2-(4-(3-chlorophenyl)piperazin-1-yl)acetamide (C19H18Cl2F3N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18Cl2F3N3O |
| Molecular Weight | 432.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- 1-(3-Chloro-5-trifluoromethyl-pyridin-2-ylmethyl)-piperidine-4-carboxylic acid (4-chloro-phenyl)-amide (CAS 1311278-10-0)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1-(4-(4-chlorophenyl)piperazin-1-yl)propan-1-one (CAS 303148-36-9)
- 2-({1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1H-imidazol-2-yl}sulfanyl)-1-(4-chlorophenyl)ethan-1-one (CAS 339276-71-0)
- 7-Chloro-11-(4-chloro-3-nitrophenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 946386-89-6)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-2-(4-chlorobenzyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-14-7)
- N-(4-Chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-2-(pyrimidin-2-ylthio)acetamide (CAS 128433-37-4)
- 2-(6-Chloro-1,1,2,2,3,3,4,4,5,5,6,6-dodecafluorohexyl)-2,3,3-trifluorooxirane (CAS 66443-82-1)
- 2-Chloro-4-methanesulfonyl-N-{4-[(4-methylphenyl)sulfanyl]phenyl}benzamide (CAS 339096-18-3)
Recommended Standards
- 2-(2-Trityl-2H-tetrazol-5-yl)phenylboronic Acid (CAS 143722-25-2)
- 2-(1-Trityl-5-tetrazolyl)phenylboronic Acid (CAS 144873-97-2)
- tert-Butyl (4-(4-amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)butyl)carbamate (CAS 1887095-79-5)
- 1,3-Dibromo-5-tetradecylbenzene (CAS 157761-91-6)
- α-Cyclodextrin hydrate (CAS 51211-51-9)
- N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-3-(methylthio)benzamide (CAS 896357-94-1)
- 5-Methyl-1,3-diphenyl-1H-pyrazole (CAS 7188-89-8)
- 5-Bromo-3-formylpicolinic acid (CAS 1289071-04-0)
- N'-(5,5-dimethyl-3-oxocyclohex-1-en-1-yl)-2-tosylacetohydrazide (CAS 1022406-91-2)
- 2-Amino-1-(furan-2-ylmethyl)-4,5,6,7-tetrahydro-1h-indole-3-carbonitrile (CAS 103026-03-5)
- 2-(4-(Difluoromethyl)-2-methoxypyridin-3-yl)acetic acid (CAS 1805311-14-1)
- 1,2,3,6-Tetragalloylglucose (CAS 79886-50-3)
- 2-bromo-N,N,3-trimethylbutanamide (CAS 959028-13-8)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com