4-(Trifluoromethoxy)benzoic Acid CAS 330-12-1
| CAS No. | 330-12-1 |
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-(Trifluoromethoxy)benzoic Acid (CAS 330-12-1), a certified reference material (molecular formula C8H5F3O3, MW 206.12 g/mol) for analytical method development and quality control.
4-(Trifluoromethoxy)benzoic Acid (C8H5F3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-(Trifluoromethoxy)benzoic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3O3 |
| Molecular Weight | 206.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Trifluoromethoxy Standards
- 2-(Trifluoromethoxy)benzoic acid (CAS 150436-84-3)
- 2-(Trifluoromethoxy)benzoic Acid (CAS 1979-29-9)
- 5-(Trifluoromethoxy)salicylaldehyde (CAS 93249-62-8)
- (1s)-1-[4-(trifluoromethoxy)phenyl]ethan-1-ol (CAS 1108723-47-2)
- 1-Phenyl-2-(trifluoromethoxy)ethan-1-ol (CAS 1171146-29-4)
- (2-Methyl-5-(trifluoromethoxy)phenyl)methanol (CAS 1261478-61-8)
- (4-Methyl-2-(trifluoromethoxy)phenyl)methanol (CAS 1261683-64-0)
- (3-Methyl-4-(trifluoromethoxy)phenyl)methanol (CAS 1261747-68-5)
Recommended Standards
- 4-methyl-5-nitro-2-(trifluoromethyl)pyridine (CAS 944317-53-7)
- 4-Hydroxy-6-(trifluoromethyl)picolinamide (CAS 924871-44-3)
- 5-Amino-2-(trifluoromethyl)isonicotinic acid (CAS 944900-27-0)
- 4-Hydroxy-3-(trifluoromethyl)benzoic Acid (CAS 220239-68-9)
- 3,4-Difluoro-2,6-dimethylaniline (CAS 2407072-62-0)
- Prasugrel D4 (CAS 1189919-49-0)
- 2-(Amino)propanediamide hydrochloride 15N3 (CAS 914799-40-9)
- n-Cyclopropyl-2-((2-methyl-3-nitrophenyl)amino)acetamide (CAS 923248-69-5)
- 2-Methylquinoline-5-carbaldehyde (CAS 141234-07-3)
- 3-[4-(methylthio)phenyl]-1,2,4-thiadiazol-5-amine (CAS 889940-61-8)
- 3-Amino-1,1,1-trifluorobutan-2-ol hydrochloride (CAS 115363-79-6)
- 2-Ethoxyphenyl isothiocyanate (CAS 23163-84-0)
- 4-Chloro-2-fluoro-3-(propan-2-yloxy)phenol (CAS 1881320-46-2)
- Heptapeptide-6 (CAS CATO-CPTD788823)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com