2-(4-Chloro-3-fluorophenoxy)acetic acid CAS 331-41-9
| CAS No. | 331-41-9 |
| Molecular Formula | C8H6ClFO3 |
| Molecular Weight | 204.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(4-Chloro-3-fluorophenoxy)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-(4-Chloro-3-fluorophenoxy)acetic acid (CAS 331-41-9), a certified reference material (molecular formula C8H6ClFO3, MW 204.58 g/mol) for analytical method development and quality control.
The molecular framework of 2-(4-Chloro-3-fluorophenoxy)acetic acid (C8H6ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClFO3 |
| Molecular Weight | 204.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-4-fluoro-3-methoxybenzoic acid (CAS 1055968-55-2)
- 4-Chloro-2-fluoro-6-methoxybenzoic acid (CAS 1082042-25-8)
- 4-Chloro-2-fluoro-3-methoxybenzoic acid (CAS 1169870-80-7)
- 2-(2-Chloro-3-fluorophenyl)-2-hydroxyacetic acid (CAS 1214345-50-2)
- 4-Chloro-2-fluoromandelic Acid (CAS 1214345-56-8)
- 2-(5-Chloro-2-fluorophenyl)-2-hydroxyacetic acid (CAS 1214345-65-9)
- 2-(4-Chloro-3-fluorophenyl)-2-hydroxyacetic acid (CAS 1214376-99-4)
- 2-(3-Chloro-4-fluorophenyl)-2-hydroxyacetic acid (CAS 1214377-83-9)
Recommended Standards
- 2-(4-Chloro-2-fluorophenoxy)acetic acid (CAS 326-75-0)
- 2-Chloro-4-ethynyl-1-(trifluoromethyl)benzene (CAS 2229409-91-8)
- 2-(3-Chloro-4-fluorophenoxy)acetic acid (CAS 331-40-8)
- 2-Chloro-5-fluoro-3-hydroxy-4-methoxybenzaldehyde (CAS 2872659-30-6)
- n-(6-Bromopyridin-2-yl)cyclobutanecarboxamide (CAS 1153898-24-8)
- (1-((3-Fluorophenyl)sulfonyl)pyrrolidin-3-yl)methanamine (CAS 1832067-64-7)
- (E)-Ethyl 3-(3-bromopyridin-4-yl)acrylate (CAS 2660181-37-1)
- n-Cyclopropyl-2-((2,4-dimethylphenyl)amino)acetamide (CAS 923688-99-7)
- 5,6-Dimethoxy-1H-benzoimidazole (CAS 72721-02-9)
- 1-Benzothiophen-5-ylhydrazine (CAS 45891-43-8)
- N-allyl-6-(((4-chlorophenyl)thio)methyl)-2-phenylpyrimidin-4-amine (CAS 477867-16-6)
- 4-Hydroxybenzo[d]isoxazole-3-carboxylic acid (CAS 57764-43-9)
- Methyl 3-chloro-5h,6h,7h,8h-pyrido[4,3-c]pyridazine-6-carboxylate (CAS 39716-01-3)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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