(E)-[(2-Methoxyphenyl)methylidene]amino 4-fluorobenzoate CAS 331460-34-5
| CAS No. | 331460-34-5 |
| Molecular Formula | C15H12FNO3 |
| Molecular Weight | 273.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-[(2-Methoxyphenyl)methylidene]amino 4-fluorobenzoate.
CATO supplies (E)-[(2-Methoxyphenyl)methylidene]amino 4-fluorobenzoate (CAS 331460-34-5), a certified reference material (molecular formula C15H12FNO3, MW 273.26 g/mol) for analytical method development and quality control.
(E)-[(2-Methoxyphenyl)methylidene]amino 4-fluorobenzoate (C15H12FNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H12FNO3 |
| Molecular Weight | 273.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- 7-(4-Methoxyphenyl)-1,7-dihydrotetrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 515824-23-4)
- (2-Methoxyphenyl)methyl N-[(E)-2-(furan-2-yl)ethenyl]carbamate (CAS 338399-82-9)
- 4-(4-Methoxyphenyl)-2-nitrobenzoic acid (CAS 669002-29-3)
- 4-(3-Methoxyphenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1193052-26-4)
- 4-(2-Methoxyphenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1214182-75-8)
- 2-(4-Methoxyphenyl)-6-methyl-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid (CAS 1707378-79-7)
- 4-(4-Methoxyphenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 178324-01-1)
- 3-(N-(3-methoxyphenyl)sulfamoyl)-2-methylpropanoic acid (CAS 1018528-60-3)
Recommended Standards
- (7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)(4-fluorophenyl)methanone (CAS 914350-54-2)
- (E)-4-((4-((difluoromethyl)thio)phenyl)amino)-4-oxobut-2-enoic acid (CAS 301313-36-0)
- (R)-(2-Methyloxiran-2-yl)methyl 4-nitrobenzenesulfonate (CAS 683276-64-4)
- [(4Z)-4,5,6,7-Tetrahydro-1-benzofuran-4-ylidene]amino 4-fluorobenzoate (CAS 478042-35-2)
- 3-(2-Chloroethyl)-8-oxa-3-azabicyclo[3.2.1]Octane (CAS 1432792-65-8)
- 2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-N'-(2-cyanoethanimidoyl)acetohydrazide (CAS 338979-35-4)
- 2-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethyl (4-nitrophenyl) carbonate (CAS 1345681-74-4)
- Ethyl 4-Boc-2-morpholinecarboxylate (CAS 768371-16-0)
- N-[4-(Piperidine-1-sulfonyl)-phenyl]-succinamic acid (CAS 314764-11-9)
- N-methyl-4-sulfamoylbenzamide (CAS 10518-85-1)
- 3-(3-Bromo-phenoxy)-propionic acid (CAS 18386-03-3)
- (S)-Benzyl (1-(2-chloroacetyl)pyrrolidin-3-yl)carbamate (CAS 1354001-95-8)
- N-(1-Acetylindolin-6-yl)-4-phenylbutanamide (CAS 1021209-80-2)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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