(2Z)-3-(4-Chlorophenyl)-N-(5-fluoro-2-methylphenyl)prop-2-enamide CAS 331461-55-3

Purity 97%+In StockPharmaceutical Standards
CAS No.331461-55-3
Molecular FormulaC16H13ClFNO
Molecular Weight289.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2Z)-3-(4-Chlorophenyl)-N-(5-fluoro-2-methylphenyl)prop-2-enamide CAS 331461-55-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 289.73 g/mol gives (2Z)-3-(4-Chlorophenyl)-N-(5-fluoro-2-methylphenyl)prop-2-enamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

(2Z)-3-(4-Chlorophenyl)-N-(5-fluoro-2-methylphenyl)prop-2-enamide (CAS 331461-55-3), molecular formula C16H13ClFNO and molecular weight 289.73 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (2Z)-3-(4-Chlorophenyl)-N-(5-fluoro-2-methylphenyl)prop-2-enamide (C16H13ClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), (2Z)-3-(4-Chlorophenyl)-N-(5-fluoro-2-methylphenyl)prop-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H13ClFNO
Molecular Weight289.73 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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