1-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-2-[(3-methylphenyl)sulfanyl]ethan-1-one CAS 331461-96-2
| CAS No. | 331461-96-2 |
| Molecular Formula | C22H18Cl2O2S |
| Molecular Weight | 417.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-2-[(3-methylphenyl)sulfanyl]ethan-1-one.
CATO supplies 1-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-2-[(3-methylphenyl)sulfanyl]ethan-1-one (CAS 331461-96-2), a certified reference material (molecular formula C22H18Cl2O2S, MW 417.35 g/mol) for analytical method development and quality control.
The molecular framework of 1-{4-[(3,4-dichlorophenyl)methoxy]phenyl}-2-[(3-methylphenyl)sulfanyl]ethan-1-one (C22H18Cl2O2S) is characterized by a steroid core, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H18Cl2O2S |
| Molecular Weight | 417.35 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related dichlorophenyl Standards
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Recommended Standards
- 1,7-Dimethoxyoctamethyltetrasiloxane (CAS 17928-31-3)
- 1-Phenyl-2-(2-phenylhydrazono)-3-(phenylsulfonyl)propan-1-one (CAS 7243-06-3)
- tert-Butyl 4-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)piperidine-1-carboxylate (CAS 1310383-45-9)
- 2-(((tert-Butyldimethylsilyl)oxy)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine (CAS 2760431-07-8)
- 1-(3-Isothiocyanatopropyl)-4-[5-(4-methoxyphenyl)-2-oxazolyl]pyridinium Bromide (CAS 1034443-41-8)
- Cyclohexanesulfonyl-acetic acid ethyl ester (CAS 847223-29-4)
- Diethyl 4-oxopyrrolidine-1,2-dicarboxylate (CAS 41263-42-7)
- (S)-3,4-Dimethyl-5-oxo-2,5-dihydrofuran-2-yl acetate (CAS 625111-90-2)
- Ceftolozane Impurity 33 (CAS CATO-C4X-240633)
- 3-Bromo-6-methoxy-2-methyl-5-nitropyridine (CAS 186413-76-3)
- Sodium 5-(4-(2-(5-ethylpyridin-2-yl)ethoxy)benzyl)-2,4-dioxothiazolidin-3-ide (CAS 105390-47-4)
- 7-Phenyl-7H-purine (CAS 18346-05-9)
- 5-Methyluridine-1,2,3,4,5- (CAS 159496-17-0)
- ([D?]Val?·1?)-C-Peptide (human) (CAS 1802078-41-6)
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