8-Bromo-2,4-dichloroquinazoline CAS 331647-05-3
| CAS No. | 331647-05-3 |
| Molecular Formula | C8H3BrCl2N2 |
| Molecular Weight | 277.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
8-Bromo-2,4-dichloroquinazoline (CAS 331647-05-3) is a high-purity analytical reference standard with the molecular formula C8H3BrCl2N2 and a molecular weight of 277.93 g/mol.
The molecular framework of 8-Bromo-2,4-dichloroquinazoline (C8H3BrCl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 8-Bromo-2,4-dichloroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3BrCl2N2 |
| Molecular Weight | 277.93 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 8-Bromo-4,6-dichloro-quinazoline (CAS 100948-94-5)
- 6-Bromo-4,8-dichloroquinazoline (CAS 100949-31-3)
- 6-Bromo-2,4-dichloroquinazoline (CAS 102393-82-8)
- 6-Bromo-2,7-dichloroquinazoline (CAS 1036757-08-0)
- 6-Bromo-2,3-dichloroquinoxaline (CAS 108229-82-9)
- 5-Bromo-2,3-dichloroquinoxaline (CAS 1092286-00-4)
- 7-bromo-4,6-dichloroquinazoline (CAS 1260847-61-7)
- 5-Bromo-2,4-dichloroquinazoline (CAS 134517-54-7)
Recommended Standards
- 7-Bromo-2,6-dichloroquinazoline (CAS 2385181-32-6)
- 2-(3,5-Dibromophenyl)acetaldehyde (CAS 109346-96-5)
- 7-Bromo-2,5-dichloroquinazoline (CAS 2770331-65-0)
- 5,7-Dibromo-2,3-dihydrobenzofuran (CAS 123266-59-1)
- (3-((Tetrahydro-2h-pyran-2-yl)methoxy)phenyl)boronic acid (CAS 1311185-12-2)
- Methyl 6-bromo-3-methoxypicolinate (CAS 945954-94-9)
- 2-((2-Cyanophenyl)sulfinyl)-N-methylbenzamide (CAS 477710-68-2)
- 3-Benzyl-1-(furan-2-ylmethyl)quinazoline-2,4(1H,3H)-dione (CAS 531504-06-0)
- Hexahydropyrazolo[1,2-a]pyrazole (CAS 5397-67-1)
- Methyl 5-(hydroxymethyl)tricyclo[3.3.0.0(3,7)]Octane-1-carboxylate (CAS 2445793-16-6)
- 3-(3-Methoxyphenyl)picolinonitrile (CAS 1303516-89-3)
- 5-Bromo-4-methoxy-2-(trifluoromethyl)pyrimidine (CAS 2226974-27-0)
- Darolutamide Impurity 44 (CAS CATO-C4X-310644)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com