5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 331647-99-5
| CAS No. | 331647-99-5 |
| Molecular Formula | C9H6F3N3O2 |
| Molecular Weight | 245.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 331647-99-5), a certified reference material (molecular formula C9H6F3N3O2, MW 245.16 g/mol) for analytical method development and quality control.
The molecular framework of 5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C9H6F3N3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6F3N3O2 |
| Molecular Weight | 245.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 2-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1018050-74-2)
- 5-Methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1018143-96-8)
- 3-Methyl-5-(trifluoromethyl)-3H-imidazo[4,5-b]pyridine-2-carboxylic acid (CAS 1260671-73-5)
- 3-Methyl-5-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1443279-18-2)
- 1-Methyl-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (CAS 1779765-25-1)
- 7-Methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylic acid (CAS 1782824-90-1)
- 6-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 1790365-86-4)
- 1-Methyl-7-(trifluoromethyl)-1h,2h,3h,4h-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 779352-05-5)
Recommended Standards
- 5-[4-(Trifluoromethoxy)phenyl]-1,3,4-oxadiazol-2-amine (CAS 910442-23-8)
- 5-Methyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 695191-64-1)
- 3-bromonaphthalene-2-carbaldehyde (CAS 89005-11-8)
- 8-bromonaphthalene-1-carbaldehyde (CAS 85864-82-0)
- (9H-Fluoren-9-yl)methyl pyrrolidin-3-ylcarbamate hydrochloride (CAS 1220040-24-3)
- tert-butyl 2-{[(2-aminophenyl)carbonyloxy]methyl}pyrrolidine-1-carboxylate (CAS 1240526-60-6)
- 3,5-Dichloro-2-methoxy-6-(trichloromethyl)pyridin-4-ol (CAS 176046-79-0)
- Oxazolo[3,2-a][1,3]diazepine (CAS 105066-62-4)
- Benserazide EP Impurity C (CAS 787504-88-5)
- 7-Bromoisochroman-1-one (CAS 1394180-31-4)
- 5-Chloro-2-(((1,2,5-trimethyl-1H-pyrrol-3-yl)methylene)amino)phenol (CAS 593272-56-1)
- Ethyl 3-(2-bromo-4-(trifluoromethyl)phenyl)propanoate (CAS 1261645-95-7)
- 8-(3-chloropropyl)-1,4-dioxaspiro[4.5]decane-8-carbonitrile (CAS CATO-C3D-262385)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
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