3-(4-Acetamidophenyl)-3-methylbutanoic acid CAS 33214-72-1
| CAS No. | 33214-72-1 |
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(4-Acetamidophenyl)-3-methylbutanoic acid (CAS 33214-72-1), a certified reference material (molecular formula C13H17NO3, MW 235.28 g/mol) for analytical method development and quality control.
The molecular framework of 3-(4-Acetamidophenyl)-3-methylbutanoic acid (C13H17NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17NO3 |
| Molecular Weight | 235.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 1 |
Related Acetamidophenyl Standards
- 4-(4-Acetamidophenyl)-4-oxobutanoic acid (CAS 5473-15-4)
- Ethyl 2-(2-acetamidophenyl)-2-oxoacetate (CAS 7671-90-1)
- N-(3-acetamidophenyl)pivalamide (CAS 521300-04-9)
- N-(4-Acetamidophenyl)-2-ethoxyacetamide (CAS 600140-39-4)
- n-(4-Acetamidophenyl)-3-methylbutanamide (CAS 349574-58-9)
- N-(4-acetamidophenyl)-3-oxobutanamide (CAS 4433-78-7)
- 4-(4-Acetamidophenyl)-2-aminothiazole (CAS 21674-96-4)
- n-(4-Acetamidophenyl)-3-methylbut-2-enamide (CAS 900711-62-8)
Recommended Standards
- 3-(4-(Diethylamino)-2-hydroxyphenyl)acrylic acid (CAS 200887-22-5)
- 3-(4-Methoxyphenyl)quinoline (CAS 57479-32-0)
- 3-(3-Methoxyazetidin-1-yl)-2-phenylpropanoic acid (CAS 1986884-61-0)
- 3-(5-Amino-1-(2-hydroxyethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol (CAS 700355-08-4)
- 5-bromo-1-methyl-3-[[5-[(2R)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]-2-pyridyl]amino]pyridin-2-one (CAS 1433860-44-6)
- 1-(5-Aminopyridin-2-yl)-3-(trifluoromethyl)-1h-pyrazol-5(4H)-one (CAS 1182794-13-3)
- (2,6-Bis((di(piperidin-1-yl)phosphino)amino)phenyl)palladium(II) chloride (CAS 955035-37-7)
- N-(2-(benzyloxy)ethyl)propan-2-amine (CAS 768357-96-6)
- 3-amino-1H-Pyrazolo[4,3-b]pyridine-5-carboxamide (CAS 2407051-44-7)
- 2-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-4-(thiophen-2-yl)pyrimidine (CAS 477862-43-4)
- Ilaprazole Impurity 47 (CAS CATO-C4X-113047)
- Decyl acrylate (CAS 2156-96-9)
- 4-Amino-3-fluorobenzonitrile (CAS 63069-50-1)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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