N-(4'-Chloro-[1,1'-biphenyl]-4-yl)-2-(4-chlorophenyl)quinoline-4-carboxamide CAS 332157-22-9
| CAS No. | 332157-22-9 |
| Molecular Formula | C28H18Cl2N2O |
| Molecular Weight | 469.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4'-Chloro-[1,1'-biphenyl]-4-yl)-2-(4-chlorophenyl)quinoline-4-carboxamide (C28H18Cl2N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
N-(4'-Chloro-[1,1'-biphenyl]-4-yl)-2-(4-chlorophenyl)quinoline-4-carboxamide (CAS 332157-22-9), molecular formula C28H18Cl2N2O and molecular weight 469.36 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H18Cl2N2O |
| Molecular Weight | 469.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
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- Dolastatin 15 (CAS 123884-00-4)
- 2,4-Dichloro-N-(3-formylphenyl)benzamide (CAS 568543-69-1)
- 2-[2-(1,4-Diazepan-1-yl)ethyl]-2,3-dihydro-1h-isoindole-1,3-dione (CAS 1097792-28-3)
- 1-(3-Chlorophenyl)-N-methyl-1-(pyrrolidin-1-yl)propan-1-amine dihydrochloride (CAS 1159825-70-3)
- 2-(Methylthio)-3-(o-tolyl)-3,5-dihydro-4H-pyrimido[5,4-b]indol-4-one (CAS 888435-88-9)
- Tetrindole Mesylate (CAS 170964-68-8)
- Bictegravir sodium (CAS 1807988-02-8)
- 2-(Pyridin-4-yloxy)ethan-1-amine hydrochloride (CAS 1992956-33-8)
- 1，2-Dimethyl hydrazine (CAS 540-73-8)
- Mitogenic Pentapeptide (CAS 87173-03-3)
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