2-((3-Cyano-4-phenyl-6-(p-tolyl)pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide CAS 332171-01-4
| CAS No. | 332171-01-4 |
| Molecular Formula | C28H23N3O2S |
| Molecular Weight | 465.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-((3-Cyano-4-phenyl-6-(p-tolyl)pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 332171-01-4) is a high-purity analytical reference standard with the molecular formula C28H23N3O2S and a molecular weight of 465.57 g/mol.
The molecular framework of 2-((3-Cyano-4-phenyl-6-(p-tolyl)pyridin-2-yl)thio)-N-(2-methoxyphenyl)acetamide (C28H23N3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C28H23N3O2S |
| Molecular Weight | 465.57 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cyano Standards
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(m-tolyl)acetamide (CAS 334497-71-1)
- 2-((3-Cyano-4-(4-methoxyphenyl)-6-phenylpyridin-2-yl)thio)-N-(o-tolyl)acetamide (CAS 339156-60-4)
- 2-((3-Cyano-6-(4-ethoxyphenyl)-4-phenylpyridin-2-yl)thio)-N-phenylacetamide (CAS 332375-85-6)
- 2-((3-Cyano-6-phenyl-4-(p-tolyl)pyridin-2-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 332128-10-6)
- Cyano(3-phenoxyphenyl)methyl 3-ethyl-2-methoxy-4-((methylsulfinyl)oxy)benzoate (CAS 956977-50-7)
- 3-(2-Cyano-4,5-dimethoxyphenyl)-1-[4-(4-pentylcyclohexyl)phenyl]thiourea (CAS 692287-55-1)
- 2-Cyano-N-(4-nitrophenyl)-2-(triphenylphosphoranylidene)acetamide (CAS 919365-93-8)
- N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)-3-(trifluoromethyl)benzamide (CAS 477866-74-3)
Recommended Standards
- (4S)-4-(Adamantan-1-yl)-2-(2-(diphenylphosphanyl)phenyl)-4,5-dihydrooxazole (CAS 944836-03-7)
- 3-Amino-4-(4-methoxyphenyl)-N-phenyl-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 333777-86-9)
- O-tert-Butyl-3-keto Fluvastatin (CAS 194934-95-7)
- 3-Amino-N-(2-methoxyphenyl)-4-phenyl-6-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 332171-23-0)
- 2-methyl-6-(propan-2-yl)pyridine-3-carboxylic acid hydrochloride (CAS 1803592-94-0)
- (S)-2-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID METHYL ESTER 51987-73-6 AS06714 L-Boc-phenyl-alanine methyl ester L-PHENYLALANINE, N-[(1,1-DIMETHYLETHOXY)CARBONYL]-, METHYL ESTER METHYL (2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-PHENYLPROPANOATE N-(TERT-BUTOXYCARBONYL)-L-PHENYLALANINE METHYL ESTER N-BOC-L-PHENYLALANINE METHYL ESTER (CAS 51987-73-6)
- N,N-dimethyl-1H-pyrazolo[4,3-d]pyrimidin-7-amine (CAS 5444-24-6)
- Methyl 2-fluoro-4-formylbenzoate (CAS 85070-58-2)
- 3-(4-Methylphenyl)-2H,4H,5H,6H-cyclopenta[c]pyrazole (CAS 400077-08-9)
- 4-(2,5-Dimethylphenoxy)-3-(trifluoromethyl)aniline (CAS 946697-58-1)
- Bilastine Impurity 65 (CAS CATO-C4X-225365)
- (4-(3-(Ethoxycarbonyl)piperidine-1-carbonyl)phenyl)boronic acid (CAS 1150114-74-1)
- (2-Hydroxy-3,5-dimethylphenyl)boronic acid (CAS 259209-23-9)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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