2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-ethylphenyl)acetamide CAS 332380-84-4
| CAS No. | 332380-84-4 |
| Molecular Formula | C18H16ClN3O2S |
| Molecular Weight | 373.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-ethylphenyl)acetamide.
2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-ethylphenyl)acetamide (CAS 332380-84-4) is a high-purity analytical reference standard with the molecular formula C18H16ClN3O2S and a molecular weight of 373.86 g/mol.
The molecular framework of 2-((5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-ethylphenyl)acetamide (C18H16ClN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O2S |
| Molecular Weight | 373.86 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- (2-Chlorophenyl)(4-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidin-1-yl)methanone (CAS 1105208-06-7)
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- 4-(2-Chlorophenyl)-N,N-dimethyl-5-(phenylsulfonyl)pyrimidin-2-amine (CAS 339107-53-8)
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Recommended Standards
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- 1-(4-Methyl-2-(pyridin-3-yl)thiazol-5-yl)ethyl (3-chlorophenyl)carbamate (CAS 866049-63-0)
- 3-(5-(Allylthio)-4-ethyl-4H-1,2,4-triazol-3-yl)-1-(4-chlorophenyl)pyridazin-4(1H)-one (CAS 478077-59-7)
- 3-Chloro-4-iodophenol (CAS 855403-42-8)
- 2-ethyl-4,4,4-trifluorobutanoic acid (CAS 769169-19-9)
- 1-(Sec-butyl)-5-propyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1248103-00-5)
- 3-[(2-methyl-1H-imidazol-1-yl)methyl]benzonitrile (CAS 1016716-83-8)
- N-Fmoc-(3S)-3-amino-3-cyclohexylpropanoic acid (CAS 1260614-86-5)
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- (2-(4-Methoxyphenyl)-4,5-dihydrooxazole-4,4-diyl)dimethanol (CAS 91642-17-0)
- (E)-1-phenethyl-4-styrylbenzene (CAS 95166-77-1)
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