1-Chloro-3-(3,4-dimethoxyphenyl)propan-2-one CAS 33251-02-4
| CAS No. | 33251-02-4 |
| Molecular Formula | C11H13ClO3 |
| Molecular Weight | 228.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-3-(3,4-dimethoxyphenyl)propan-2-one (CAS 33251-02-4), molecular formula C11H13ClO3 and molecular weight 228.67 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 1-Chloro-3-(3,4-dimethoxyphenyl)propan-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 228.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Chloro-3-(3,4-dimethoxyphenyl)propan-2-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H13ClO3 |
| Molecular Weight | 228.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
Related Chloro Standards
- 5-Chloro-3-[(3-fluorophenyl)methyl]-1,2,4-thiadiazole (CAS 1029718-68-0)
- 5-Chloro-3-[(2-fluorophenyl)methyl]-1,2,4-thiadiazole (CAS 1029718-69-1)
- n-(3-Chloro-4-fluorophenyl)-1,3-thiazol-2-amine (CAS 1039314-85-6)
- Ethyl 2-(5-chloro-2-methoxyphenyl)acetate (CAS 1050481-78-1)
- Ethyl 2-(4-chloro-3-methoxyphenyl)acetate (CAS 1056987-17-7)
- 3-Chloro-4,5-diethoxybenzaldehyde (CAS 110732-06-4)
- 2-(5-Chloro-2-methoxyphenyl)-2-methylpropanoic acid (CAS 1183997-58-1)
- 2-Chloro-4-isopropoxybenzoic acid methyl ester (CAS 1192829-82-5)
Recommended Standards
- 1-(Chloromethyl)-3-(3,5-difluorophenyl)bicyclo[1.1.1]Pentane (CAS 2287272-15-3)
- 2-((4-Chlorophenoxy)methyl)-1,4-dioxane (CAS 327087-79-6)
- 1-(3-Chloro-6-fluorobenzo[b]thiophen-2-yl)ethanone (CAS 937642-21-2)
- 2-(2-Chloro-5-methylphenoxy)-2-methylpropanoic acid (CAS 588692-86-8)
- REP 8839 (CAS 757942-43-1)
- 4-(Methoxymethyl)benzene-1-sulfonamide (CAS 1426229-01-7)
- 5-Chloro-5,6,7,8-tetrahydroquinoline (CAS 198401-82-0)
- 1,2,4,5-Cyclohexanetetracarboxylic Dianhydride (CAS 2754-41-8)
- Vardenafil Impurity 44 (CAS CATO-C4X-101744)
- 2-(4-Fluoro-2-nitrophenyl)acetic Acid (CAS 39616-95-0)
- (2R,5R)-4-Boc-5-methylpiperazine-2-methanol (CAS 1403898-64-5)
- 3-(6-(tert-Butyl)pyridin-3-yl)acrylic acid (CAS 545393-82-6)
- 2,4-Dibromo-6-methylpyridin-3-ol (CAS 23003-29-4)
- Tau Peptide (512-525) amide trifluoroacetate salt (CAS 2022956-61-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com