4-(Bromomethyl)oxetan-2-one CAS 33282-42-7
| CAS No. | 33282-42-7 |
| Molecular Formula | C4H5BrO2 |
| Molecular Weight | 164.99 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(Bromomethyl)oxetan-2-one (CAS 33282-42-7), molecular formula C4H5BrO2 and molecular weight 164.99 g/mol, is a CATO reference standard with documented purity and traceability.
4-(Bromomethyl)oxetan-2-one (C4H5BrO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C4H5BrO2 |
| Molecular Weight | 164.99 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Br-containing |
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- n-[(1-ethyl-1h-pyrazol-4-yl)methyl]pyridine-3-carboxamide (CAS 514856-39-4)
- 2-{5,7-dimethyl-2-oxo-1h,2h-pyrazolo[1,5-a]pyrimidin-6-yl}acetic acid (CAS 1258639-52-9)
- 2-(4-(Difluoromethyl)-6-iodo-5-(trifluoromethyl)pyridin-3-yl)acetonitrile (CAS 1807155-25-4)
- 1,3-O-Isopropylidene (R)-Albuterol (2S,3S)-Di-O-toluoyl Tartrate Salt (CAS 238762-33-9)
- (3-Bromo-4-methyl-phenyl)-methyl-carbamic acid tert-butyl ester (CAS 877064-95-4)
- Semaglutide impurity 81 (CAS CATO-C4X-222681)
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