5-Methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 332851-36-2
| CAS No. | 332851-36-2 |
| Molecular Formula | C9H10F3N3O2 |
| Molecular Weight | 249.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 332851-36-2), molecular formula C9H10F3N3O2 and molecular weight 249.19 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 249.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H10F3N3O2 |
| Molecular Weight | 249.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 2-(4-(Trifluoromethyl)phenyl)pyrimidine-5-carbonitrile (CAS 1261739-77-8)
- Methyl 3-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine-1-carboxylate (CAS 1358715-37-3)
- 1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl allylcarbamate (CAS 477713-75-0)
- 2-Methyl-2-(5-(trifluoromethyl)pyridin-2-yloxy)propanoic acid (CAS 605680-62-4)
- 5-Methyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 436088-42-5)
- Ethyl 2-(4-(trifluoromethyl)pyridin-2-yl)hydrazine-1-carboxylate (CAS 883010-89-7)
- Methyl 2-(trifluoromethyl)-1,2,3,4-tetrahydroimidazo[1,5-a]pyrimidine-8-carboxylate (CAS 2137845-58-8)
- 880764-96-5 2-(Trifluoromethyl)-DL-tyrosine MFCD01320692 (CAS 880764-96-5)
Recommended Standards
- 4-fluoro-2-(furan-3-amido)benzoic acid (CAS 953742-26-2)
- 3-Amino-3-[4-(trifluoromethoxy)phenyl]propionic Acid (CAS 213192-56-4)
- 6-(Dimethoxymethyl)-5-(trifluoromethyl)nicotinaldehyde (CAS 2851874-09-2)
- 3-Amino-3-(2-(trifluoromethoxy)phenyl)propanoic acid (CAS 773122-83-1)
- 2,4-Dimethyl-2H-1,2,3-triazole (CAS 60166-44-1)
- (4aR,7aR)-tert-Butyl hexahydro-1H-pyrrolo[3,4-b]pyridine-6(2H)-carboxylate (CAS 1909294-62-7)
- 2-(1-methyl-1H-pyrrol-2-yl)acetic acid (CAS 21898-59-9)
- Ethyl 6-fluoro-4-(trifluoromethyl)nicotinate (CAS 1803801-10-6)
- 4-Chloro-N-(o-tolyl)benzamide (CAS 2447-94-1)
- 3-(3-amino-4-bromo-1H-pyrazol-1-yl)propanoic acid,HCl (CAS 1431962-69-4)
- [4,5'-Bipyrimidine]-2,2',4',6(1H,1'H,3H,3'H)-tetraone (CAS 56686-19-2)
- N-[(E)-1H-indol-3-ylmethylidene]-4H-1,2,4-triazol-4-amine (CAS 35554-74-6)
- Cyclohexyl(tetrahydro-2H-pyran-2-yl)methanone (CAS 113122-89-7)
- Semaglutide impurity 103 (CAS 1446013-07-5)
Why CATO?
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