Glipizide EP Impurity A CAS 33288-71-0
| CAS No. | 33288-71-0 |
| Molecular Formula | C14H16N4O3S |
| Molecular Weight | 320.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Glipizide EP Impurity A (C14H16N4O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Glipizide EP Impurity A (CAS 33288-71-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H16N4O3S and a molecular weight of 320.37 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Glipizide EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H16N4O3S |
| Molecular Weight | 320.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Glipizide Standards
- Glipizide EP Impurity D (CAS 1346600-54-1)
- Glipizide EP Impurity H (CAS 10080-05-4)
- Glipizide Impurity 24 (CAS CATO-C4X-140724)
- Glipizide Impurity 38 (CAS CATO-C4X-140738)
- Glipizide Impurity 45 (CAS CATO-C4X-140745)
- Glipizide Impurity 47 (CAS CATO-C4X-140747)
- Glipizide EP Impurity F (CAS 192118-08-4)
- Glipizide EP Impurity G (CAS 33288-74-3)
Recommended Standards
- Fasudil impurity 66 (CAS CATO-C4X-136566)
- (2S,4S)-4-Fluoro-1-[2-[[(1R,3S)-3-(1H-1,2,4-triazol-1-ylmethyl)cyclopentyl]amino]acetyl]-2-pyrrolidinecarbonitrile 868771-57-7 Melogliptin (CAS 868771-57-7)
- N-Acetyl Sulfamethazine (CAS 100-90-3)
- tert-butyl (2S,4R)-4-azido-2-(methylsulfonyloxymethyl)pyrrolidine-1-carboxylate (CAS 2509477-37-4)
- Cyproheptadine Impurity 16 (CAS CATO-C4X-150616)
- Butylphthalide Impurity 59 (CAS 503822-00-2)
- Atropine EP Impurity D&E (CAS CATO-C4X-14891)
- 2-(5-Fluoro-1H-inden-3-yl)acetic acid (CAS 1049800-33-0)
- Methyl 4-(4-chlorophenyl)-3-(N-(4-(ethoxycarbonyl)phenyl)sulfamoyl)thiophene-2-carboxylate (CAS 1021209-52-8)
- 4-(Chloro(phenyl)methyl)pyridine (CAS 740062-52-6)
- 5-Bromo-2-(1H-pyrrol-2-yl)-1H-indole (CAS 569337-42-4)
- 49763-65-7 Benzoyl chloride, 4-pentyl- 4-Pentylbenzoyl chloride EINECS 256-478-8 (CAS 49763-65-7)
- Pindolol EP Impurity E (CAS 2380-94-1)
- Eledoisin Related Peptide (CAS 2990-43-4)
Why CATO?
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