2-((5-(2-Methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide CAS 333312-71-3
| CAS No. | 333312-71-3 |
| Molecular Formula | C24H22N4O2S |
| Molecular Weight | 430.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-((5-(2-Methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide.
2-((5-(2-Methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide (CAS 333312-71-3) is a high-purity analytical reference standard with the molecular formula C24H22N4O2S and a molecular weight of 430.52 g/mol.
The molecular framework of 2-((5-(2-Methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide (C24H22N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((5-(2-Methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H22N4O2S |
| Molecular Weight | 430.52 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Methoxyphenyl Standards
- N-(2-methoxyphenyl)-2-((4-phenyl-5-(m-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 483350-51-2)
- 1-(4-Methoxyphenyl)-2,5,6-triphenylpyrimidin-4(1H)-one (CAS 88317-17-3)
- 2-(4-Methoxyphenyl)-1,5,6-triphenylpyrimidin-4(1H)-one (CAS 88317-20-8)
- 4-(2-Methoxyphenyl)-5-(4-(piperidin-1-ylsulfonyl)phenyl)-4H-1,2,4-triazole-3-thiol (CAS 917750-03-9)
- 2-{[(4-methoxyphenyl)methyl]sulfanyl}-4-[(4-methoxyphenyl)sulfanyl]-6-[(methylsulfanyl)methyl]pyrimidine (CAS 303984-97-6)
- 4-(4-Methoxyphenyl)-6-phenyl-2-((2-(piperidin-1-yl)ethyl)thio)nicotinonitrile (CAS 311333-16-1)
- 6-(4-Methoxyphenyl)-4-phenyl-2-((2-(piperidin-1-yl)ethyl)thio)nicotinonitrile (CAS 332376-27-9)
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Recommended Standards
- 2-((4-(n-(3,5-Dimethylphenyl)sulfamoyl)phenyl)carbamoyl)cyclohexane-1-carboxylic acid (CAS 543695-33-6)
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(2-methoxyphenyl)acetamide (CAS 332907-37-6)
- 1-(3,4-Dimethoxybenzyl)-5-ethyl-4-(1-(phenylsulfonyl)ethyl)-1,3-dihydro-2H-imidazol-2-one (CAS 439096-14-7)
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 332907-36-5)
- 8-Methoxyindolizine (CAS 195615-14-6)
- N,N-Diphenyl-[2,2':5',2'':5'',2''':5''',2''''-quinquethiophen]-5-amine (CAS 888488-92-4)
- 4-(1,1-Difluoroethyl)-1,2-difluorobenzene (CAS 1138445-09-6)
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- 2-(2,3,5-Trifluorophenyl)ethanol (CAS 1000548-51-5)
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- 2-chloro-N-(4-chlorophenyl)-1-methyl-1H-indole-3-carboxamide 478049-45-5 KS-000039VU (CAS 478049-45-5)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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