3-((3-Chloro-4-methylphenyl)amino)-1-(thiophen-2-yl)propan-1-one CAS 333352-66-2
| CAS No. | 333352-66-2 |
| Molecular Formula | C14H14ClNOS |
| Molecular Weight | 279.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-((3-Chloro-4-methylphenyl)amino)-1-(thiophen-2-yl)propan-1-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-((3-Chloro-4-methylphenyl)amino)-1-(thiophen-2-yl)propan-1-one (CAS 333352-66-2), a certified reference material (molecular formula C14H14ClNOS, MW 279.79 g/mol) for analytical method development and quality control.
3-((3-Chloro-4-methylphenyl)amino)-1-(thiophen-2-yl)propan-1-one (C14H14ClNOS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-((3-Chloro-4-methylphenyl)amino)-1-(thiophen-2-yl)propan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14ClNOS |
| Molecular Weight | 279.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-(((4-(methylthio)phenyl)amino)methyl)phenol (CAS 1019586-35-6)
- 3-Chloro-n-[phenyl(thiophen-2-yl)methyl]propanamide (CAS 1050883-84-5)
- 2-Chloro-5-(2-(pyrrolidin-1-yl)thiazol-4-yl)aniline (CAS 1443288-09-2)
- 2-Chloro-n-[(4-methylphenyl)(thiophen-2-yl)methyl]acetamide (CAS 847744-31-4)
- 6-Chloro-2-(methylthio)-N-phenethylpyrimidin-4-amine (CAS 330658-02-1)
- 6-Chloro-N-(2,3-dimethylphenyl)-2-(methylthio)pyrimidin-4-amine (CAS 86626-95-1)
- 4-Chloro-N-cyclohexyl-N-phenylbutanamide (CAS 1023536-91-5)
- 2-Chloro-N-((1-(m-tolyl)cyclohexyl)methyl)acetamide (CAS 1432680-90-4)
Recommended Standards
- 4-(4-Chlorophenyl)-2-(piperazin-1-yl)thiazole (CAS 924843-35-6)
- 5-(2-(4-Chlorophenyl)cyclopropyl)-4-ethyl-4h-1,2,4-triazole-3-thiol (CAS 828283-49-4)
- {3-[5-(Chloromethyl)-2-methanesulfonyl-1h-imidazol-1-yl]propyl}dimethylamine (CAS 1221342-74-0)
- 5-(2-Chlorophenyl)-4-cyclopentyl-4H-1,2,4-triazole-3-thiol (CAS 750610-95-8)
- 4-Chloro-5-nitro-1H-indazole (CAS 907958-42-3)
- 5-Phenoxyfuran-2-carboxylic acid (CAS 60698-32-0)
- Racemic-(3aR,6R,7aR)-4-(tert-butoxycarbonyl)octahydrofuro[3,2-b]pyridine-6-carboxylic acid (CAS 1314388-60-7)
- 1-Bromononane-9,9,9-d3 (CAS 1219799-20-8)
- Tert-butyl 3-cyano-3-(3-fluoropyridin-2-yl)azetidine-1-carboxylate (CAS 895132-49-7)
- 5-(2-(Benzo[d][1,3]dioxol-5-ylmethyl)-2H-tetrazol-5-yl)-2-methoxyaniline (CAS 1219568-58-7)
- Methyl 2-amino-2-(5-bromothiophen-3-yl)acetate hydrochloride (CAS 2137481-21-9)
- N-(1-(3-Chlorophenyl)ethyl)propan-2-amine (CAS 1019598-00-5)
- 2-(2-Fluoro-6-hydroxypyridin-4-yl)acetic acid (CAS 1227594-69-5)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com