2,6-Diamino-4-(2,3,4-trimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile CAS 333759-74-3
| CAS No. | 333759-74-3 |
| Molecular Formula | C16H16N4O3S |
| Molecular Weight | 344.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 344.39 g/mol gives 2,6-Diamino-4-(2,3,4-trimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,6-Diamino-4-(2,3,4-trimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile (CAS 333759-74-3) is a high-purity analytical reference standard with the molecular formula C16H16N4O3S and a molecular weight of 344.39 g/mol.
The molecular framework of 2,6-Diamino-4-(2,3,4-trimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile (C16H16N4O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,6-Diamino-4-(2,3,4-trimethoxyphenyl)-4H-thiopyran-3,5-dicarbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16N4O3S |
| Molecular Weight | 344.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Diamino Standards
- 4,4'-Diamino-[1,1'-biphenyl]-2,2'-disulfonic acid(contains 30% Water at maximum) (CAS 117-61-3)
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- 2,6-Diamino-5-(6-(benzo[d]oxazol-2-yl)-6-hydroxyhexyl)pyrimidin-4(1H)-one (CAS 647831-12-7)
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Recommended Standards
- 2-((5-(Furan-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 498550-72-4)
- 3-([1,1'-Biphenyl]-4-yl)-4-hydroxy-6-oxo-6,7-dihydrothieno[2,3-b]pyridine-5-carbonitrile (CAS 844499-68-9)
- 2-((1-(4-Methoxyphenyl)-1H-imidazol-2-yl)thio)-N-(5-methylisoxazol-3-yl)acetamide (CAS 851132-60-0)
- 4,4-(Benzo[c][1,2,5]thiadiazole-4,7-diyl)dibenzaldehyde (CAS 914651-17-5)
- (S)-2-Amino-N-(2-bromobenzyl)-N-ethyl-3-methylbutanamide (CAS 1354016-44-6)
- (6-Ethylpyridin-2-yl)boronic acid (CAS 1365066-78-9)
- 2,5-Dimethyl-9H-carbazole (CAS 78787-79-8)
- 3-((Dimethylamino)methyl)dihydro-2H-pyran-4(3H)-one (CAS 132630-69-4)
- 7-Chloroimidazo[1,2-a]pyridin-2-amine (CAS 1501148-82-8)
- 2-(2,6-dioxo-3-piperidyl)-5-[2-(2-hydroxyethoxy)ethyl]isoindoline-1,3-dione (CAS 2357111-02-3)
- Etoricoxib Impurity 52 (CAS CATO-C4X-108052)
- 6-Nitro-2,3-diphenylquinoxaline (CAS 7466-45-7)
- 2,4-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-pyrazole (CAS 1047644-76-8)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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