5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid CAS 333765-71-2
| CAS No. | 333765-71-2 |
| Molecular Formula | C14H12F3N3O2 |
| Molecular Weight | 311.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 333765-71-2), molecular formula C14H12F3N3O2 and molecular weight 311.26 g/mol, is a CATO reference standard with documented purity and traceability.
5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid (C14H12F3N3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 5-Phenyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H12F3N3O2 |
| Molecular Weight | 311.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
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- 2-((1-Methyl-5-(trifluoromethyl)-1H-pyrazol-3-yl)methyl)-3a,7a-dihydro-1H-isoindole-1,3(2H)-dione (CAS 1354703-89-1)
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Recommended Standards
- 5-((4-Methoxybenzyl)oxy)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbonitrile (CAS 318469-09-9)
- 6-Oxo-1-[3-(trifluoromethyl)benzyl]-1,6-dihydro-3-pyridinecarbohydrazide (CAS 477852-89-4)
- 4-Methoxy-N-(4-(trifluoromethoxy)phenyl)benzamide (CAS 424809-73-4)
- Ethyl 4-((5-(trifluoromethyl)pyridin-2-yl)oxy)benzoate (CAS 866154-36-1)
- Rel-(1R,2S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl formate (CAS 7492-41-3)
- (1-Benzyl-3,3-difluoropiperidin-4-yl)methanol (CAS 1303974-07-3)
- Niobium(V) oxide (CAS 1313-96-8)
- 2-(4-Formylphenyl)-N-methylacetamide (CAS 1976020-58-2)
- 4-Trifluoromethyl-1H-imidazole (CAS 33468-69-8)
- 5-Iodo-2-methoxy-1,3-dimethylbenzene (CAS 55215-54-8)
- Benzyl (1-(tert-butyl)-3-((1R,3S)-3-hydroxycyclopentyl)-1H-pyrazol-5-yl)carbamate (CAS 2460255-81-4)
- Binucleine 2 (CAS 220088-42-6)
- Methyl 2-(5-methyl-1H-imidazol-1-yl)acetate (CAS 379228-99-6)
- Tau Peptide (306-336) (Repeat 3 Domain) trifluoroacetate salt (CAS 330456-26-3)
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