5-(5-Bromothiophen-2-yl)thiophene-2-carboxylic acid CAS 3339-81-9
| CAS No. | 3339-81-9 |
| Molecular Formula | C9H5BrO2S2 |
| Molecular Weight | 289.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 289.17 g/mol gives 5-(5-Bromothiophen-2-yl)thiophene-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-(5-Bromothiophen-2-yl)thiophene-2-carboxylic acid (CAS 3339-81-9), molecular formula C9H5BrO2S2 and molecular weight 289.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(5-Bromothiophen-2-yl)thiophene-2-carboxylic acid (C9H5BrO2S2) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(5-Bromothiophen-2-yl)thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5BrO2S2 |
| Molecular Weight | 289.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 2 |
Related Bromothiophen Standards
- 6-(5-Bromothiophen-2-yl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 1485644-56-1)
- 1-(2-(5-Bromothiophen-2-yl)ethyl)-3-cyclopropylurea (CAS 1240958-02-4)
- 1-((4-Bromothiophen-2-yl)methyl)pyrrolidine-2-carboxamide (CAS 1248730-02-0)
- (3-Bromothiophen-2-yl)(5-methylthiophen-2-yl)methanol (CAS 1344017-76-0)
- 1-(4-Bromothiophen-2-yl)-N-(thiazol-5-ylmethyl)methanamine (CAS 1344301-95-6)
- 2-(3-(5-Bromothiophen-2-yl)-1,2,4-oxadiazol-5-yl)acetic acid (CAS 1340308-50-0)
- (1-((5-Bromothiophen-2-yl)methyl)piperidin-3-yl)methanamine (CAS 1019457-89-6)
- n-((4-Bromothiophen-2-yl)methyl)-1-methylpiperidin-4-amine (CAS 1096850-13-3)
Recommended Standards
- 5-(4-Bromobenzenesulfinyl)-1,2,3-thiadiazole (CAS 338397-21-0)
- 5-(Methoxycarbonyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 916212-10-7)
- 3-Bromo-3,5-dimethylbenzophenone (CAS 844879-51-2)
- 5-Bromo-N-(thiazol-2-yl)thiophene-2-carboxamide (CAS 313404-40-9)
- 6-Methyl-[1,2,4]triazolo[4,3-b]pyridazine-3-thiol (CAS 89418-40-6)
- 3-Chloro-5-(trifluoromethoxy)-1H-indazole (CAS 1446406-93-4)
- 2-(5,6-Dihydro-4H-pyrrolo[1,2-b]pyrazol-2-yl)butanoic acid (CAS 1529598-48-8)
- Methyl 2-(5-bromopyrimidin-2-yl)-2-methylpropanoate (CAS 1364718-88-6)
- 8-(3-Aminopyrrolidin-1-yl)-2-(4-fluorobenzyl)-[1,2,4]triazolo[4,3-a]pyrazin-3(2H)-one (CAS 1710833-87-6)
- 1-(4-Fluorophenyl)-3-((2,3,4,5,6-pentamethylbenzyl)thio)propan-1-one (CAS 882749-16-8)
- 1-Methyl-4-(2-piperidin-2-yl-ethyl)-piperazine (CAS 856843-58-8)
- n-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)cyclopropanamine (CAS 1150271-52-5)
- (S)-(+)-Indoline-2-Methanol (S)-indolin-2-ylmethanol 27640-33-1 (CAS 27640-33-1)
- Peptide Impurity (CAS CATO-CPTD788810)
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