tert-Butyl 4-(4-fluorophenoxy)piperidine-1-carboxylate CAS 333954-85-1
| CAS No. | 333954-85-1 |
| Molecular Formula | C16H22FNO3 |
| Molecular Weight | 295.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including tert-Butyl 4-(4-fluorophenoxy)piperidine-1-carboxylate.
CATO supplies tert-Butyl 4-(4-fluorophenoxy)piperidine-1-carboxylate (CAS 333954-85-1), a certified reference material (molecular formula C16H22FNO3, MW 295.35 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, tert-Butyl 4-(4-fluorophenoxy)piperidine-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 295.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H22FNO3 |
| Molecular Weight | 295.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl 4-(2-fluorophenyl)-4-hydroxypiperidine-1-carboxylate (CAS 403806-35-9)
- Tert-butyl 4-(5-amino-3-fluoropyridin-2-yl)piperidine-1-carboxylate (CAS 2351275-60-8)
- tert-Butyl 4-(2-fluorophenoxy)piperidine-1-carboxylate (CAS 944808-08-6)
- tert-butyl N-[(tert-butoxy)carbonyl]-N-methanesulfonylcarbamate (CAS 2092000-74-1)
- 3-Bromo-4-(4-fluorophenoxy)benzene-1-sulfonyl chloride (CAS 1283859-52-8)
- 3-(Cyanomethyl)-4-nitrobenzoic acid (CAS 104825-21-0)
- 1-Phenethyl-4-phenyl-1,2,3,4-tetrahydronaphthalene (CAS 40542-33-4)
- Eicosapentaenoyl 1-Propanol-2-amide (CAS 1638355-66-4)
- 2-{[4-Methyl-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(2-nitrophenyl)acetamide (CAS 802958-07-2)
- 3-Formyl-5-methoxy-1H-indole-2-carbonitrile (CAS 62542-48-7)
- N-(2,4-dimethoxyphenyl)-N-((2-nitrophenyl)sulfonyl)glycine (CAS 357389-73-2)
- 2-((2-Methylbutyl)amino)cyclohexan-1-ol (CAS 1247839-60-6)
- 4-{[(4-chlorophenyl)sulfanyl]methyl}-6-[(2,4-dichlorophenyl)methoxy]-2-methylpyrimidine (CAS 338960-39-7)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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