2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione CAS 3343-28-0
| CAS No. | 3343-28-0 |
| Molecular Formula | C13H9NO5 |
| Molecular Weight | 259.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 259.21 g/mol gives 2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione (CAS 3343-28-0) is a high-purity analytical reference standard with the molecular formula C13H9NO5 and a molecular weight of 259.21 g/mol.
The molecular framework of 2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione (C13H9NO5) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H9NO5 |
| Molecular Weight | 259.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Dioxotetrahydro Standards
- (R)-2-(2,6-Dioxotetrahydro-2H-pyran-3-yl)isoindoline-1,3-dione (CAS 25830-78-8)
- 4-(1,3-Dioxotetrahydro-1H-pyrrolo[1,2-c]imidazol-2(3H)-yl)benzoic acid (CAS 1219375-49-1)
- 3-(2,6-Dioxotetrahydro-2H-pyran-3-yl)propanoic acid (CAS 40550-18-3)
- N-(2,5-Dioxotetrahydro-3-furanyl)-4-methoxybenzamide (CAS 1269446-37-8)
- (4-(4-Methyl-2,6-dioxotetrahydro-2H-4lambda4,8lambda4-[1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborol-8-yl)phenyl)boronate (CAS 1104665-01-1)
- N-(2,5-Dioxotetrahydro-3-furanyl)-4-fluorobenzamide (CAS 1269443-55-1)
- N-(2,5-Dioxotetrahydro-3-furanyl)-4-methylbenzamide (CAS 1269442-84-3)
- N-(2,5-Dioxotetrahydro-3-furanyl)-3-thiophenecarboxamide (CAS 1269443-80-2)
Recommended Standards
- 1-Bromo-4-[(3-methylbutyl)thio]benzene (CAS 76542-20-6)
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- 2-(Benzo[d][1,3]dioxol-5-yloxy)nicotinic acid (CAS 214758-41-5)
- Ilexoside D (CAS 109008-27-7)
- Methyl 2-(1H-1,3-benzodiazol-2-yl)acetate hydrochloride (CAS 1052528-15-0)
- 2-[(1R)-1-Hydroxyethyl]-3,4-dihydroquinazolin-4-one (CAS 129893-49-8)
- 2-(4-Hydroxy-2-phenylthiazol-5-yl)acetic acid (CAS 133834-03-4)
- 3-Ethyl-2-pentanone (CAS 6137-03-7)
- Calcium tetraborate (CAS 12007-56-6)
- 3-(1-Oxopropoxy)-pregnan-20-one (CAS 171494-53-4)
- Methyl 5-bromo-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 1591827-38-1)
- 5-chloro-3H-spiro[isobenzofuran-1,4'-piperidin]-3-one hydrochloride (CAS 1956318-12-9)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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