3-(3,4-Dichlorophenyl)piperazin-2-one CAS 334477-10-0
| CAS No. | 334477-10-0 |
| Molecular Formula | C10H10Cl2N2O |
| Molecular Weight | 245.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(3,4-Dichlorophenyl)piperazin-2-one (CAS 334477-10-0) is a high-purity analytical reference standard with the molecular formula C10H10Cl2N2O and a molecular weight of 245.11 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 3-(3,4-Dichlorophenyl)piperazin-2-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 245.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10Cl2N2O |
| Molecular Weight | 245.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichlorophenyl Standards
- (S)-3-(2,4-Dichlorophenyl)piperazin-2-one (CAS 1228571-52-5)
- (R)-3-(2,6-Dichlorophenyl)piperazin-2-one (CAS 1240582-12-0)
- 1-(2,4-Dichlorophenyl)piperazin-2-one (CAS 907972-71-8)
- 1-(2,6-Dichlorophenyl)piperazin-2-one (CAS 907972-75-2)
- 1-(3,5-Dichlorophenyl)piperazin-2-one (CAS 907972-79-6)
- 1-(2,6-Dichlorophenyl)cyclobutanecarboxylic Acid (CAS 1039951-74-0)
- 1-(2,5-Dichlorophenyl)pentane-1,3-dione (CAS 1040034-09-0)
- 1-(2,4-Dichlorophenyl)pentane-1,3-dione (CAS 1040073-12-8)
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