(R)-1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine CAS 334477-60-0
| CAS No. | 334477-60-0 |
| Molecular Formula | C11H11F6N |
| Molecular Weight | 271.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine (CAS 334477-60-0), molecular formula C11H11F6N and molecular weight 271.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, (R)-1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 271.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11F6N |
| Molecular Weight | 271.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (3-Fluoro-4-nitrophenyl)methylene diacetate (CAS 211388-77-1)
- {2-[(3-bromophenyl)amino]ethyl}diethylamine (CAS 52158-54-0)
- 6-Amino-1-(3-(trifluoromethyl)phenyl)pyrimidine-2,4(1H,3H)-dione (CAS 19136-40-4)
- 1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethan-1-amine (CAS 290297-43-7)
- 5-Cyclopropylfuran-2-carbaldehyde (CAS 39763-81-0)
- N-(2-(2,4-Dioxothiazolidin-3-yl)cyclohexyl)-2-methoxynicotinamide (CAS 1206994-41-3)
- 5-(4-Bromophenyl)-1,2,4-triazine-3-thiol (CAS 98592-15-5)
- Methyl 1-(4-chlorophenyl)-4-hydrazinyl-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 338418-80-7)
- 7-Bromo-4-chloro-1-benzofuran (CAS 325486-41-7)
- 2,2'-Dibromo-4,4',5,5'-tetramethoxy-1,1'-biphenyl (CAS 62012-50-4)
- 2-Chloro-4-(trifluoromethyl)thiazole-5-carbaldehyde (CAS 1823904-66-0)
- (R)-2-(4-(tert-Butyl)benzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 1049728-56-4)
- N-{3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-2-oxo-1,2-dihydropyridin-1-yl}-3-[(4-fluorophenyl)methoxy]thiophene-2-carboxamide (CAS 672949-10-9)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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