5-Chloro-2-(2-fluoroethoxy)benzoic acid CAS 334652-74-3
| CAS No. | 334652-74-3 |
| Molecular Formula | C9H8ClFO3 |
| Molecular Weight | 218.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-Chloro-2-(2-fluoroethoxy)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-Chloro-2-(2-fluoroethoxy)benzoic acid (CAS 334652-74-3), molecular formula C9H8ClFO3 and molecular weight 218.61 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system, 5-Chloro-2-(2-fluoroethoxy)benzoic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 218.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H8ClFO3 |
| Molecular Weight | 218.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-(3-Chloro-5-fluoro-4-methoxyphenyl)acetic acid (CAS 1000544-65-9)
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- 6-Chloro-2-fluoro-3-methoxyphenylacetic acid (CAS 1017777-83-1)
- 3-Chloro-4-ethoxy-5-fluorobenzoic acid (CAS 1017778-72-1)
- 3-(2-Chloro-6-fluorophenyl)-2-hydroxypropanoic acid (CAS 1181561-52-3)
- Methyl 2-(4-chloro-3-fluorophenyl)-2-hydroxyacetate (CAS 1248821-36-4)
- 3-(2-Chloro-6-fluorophenyl)-3-hydroxypropanoic acid (CAS 1249515-00-1)
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Recommended Standards
- 4-Chloro-2-ethoxy-3-fluorobenzoic acid (CAS 2385654-99-7)
- 5-Chloro-2-fluoro-4-(methoxymethoxy)benzaldehyde (CAS 2179038-42-5)
- 3-Chloro-5-fluoro-4-(methoxymethoxy)benzaldehyde (CAS 2179038-34-5)
- 6-Chloro-2-fluoro-3-(methoxymethoxy)benzaldehyde (CAS 2179038-26-5)
- 4-Cyclopentylpyrrolidine-2-carboxylic acid hydrochloride (CAS 2137472-11-6)
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- 2-(2,4-Dimethylphenoxy)-4-methoxypyridine-3-carbonitrile (CAS 339016-73-8)
- 4-Hydroxy-2-mercaptopyrazolo[1,5-a][1,3,5]triazine-8-carbonitrile (CAS 948575-58-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com