2-[4-(4-Chlorobenzenesulfonyl)piperazin-1-yl]pyrimidine CAS 334973-48-7
| CAS No. | 334973-48-7 |
| Molecular Formula | C14H15ClN4O2S |
| Molecular Weight | 338.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-[4-(4-Chlorobenzenesulfonyl)piperazin-1-yl]pyrimidine.
2-[4-(4-Chlorobenzenesulfonyl)piperazin-1-yl]pyrimidine (CAS 334973-48-7), molecular formula C14H15ClN4O2S and molecular weight 338.81 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, 2-[4-(4-Chlorobenzenesulfonyl)piperazin-1-yl]pyrimidine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 338.81 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H15ClN4O2S |
| Molecular Weight | 338.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Chlorobenzenesulfonyl Standards
- 2-(4-Chlorobenzenesulfonyl)-1-(4-hydroxy-3,5-dimethylphenyl)ethan-1-one (CAS 344279-24-9)
- 2-(3-Chlorobenzenesulfonyl)-N-(4-methoxyphenyl)acetamide (CAS 339097-23-3)
- 3-(4-Chlorobenzenesulfonyl)-6-fluoro-1,4-dihydroquinolin-4-one (CAS 866727-75-5)
- 5-(4-Chlorobenzenesulfonyl)-4-phenyl-1,2,3-thiadiazole (CAS 206132-50-5)
- (2E)-2-(4-Chlorobenzenesulfonyl)-3-(4-methoxyphenyl)prop-2-enenitrile (CAS 803703-33-5)
- 5-(4-Chlorobenzenesulfonyl)-2-methyl-4-phenylpyrimidine (CAS 339108-35-9)
- 1-(4-Chlorobenzenesulfonyl)-2-(4-chlorophenyl)propan-2-ol (CAS 338774-91-7)
- (2Z)-2-(4-Chlorobenzenesulfonyl)-3-[4-(dimethylamino)phenyl]prop-2-enenitrile (CAS 804515-70-6)
Recommended Standards
- 2-(4-Methyl-2-(methylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)ethyl 3-chlorobenzoate (CAS 338401-98-2)
- 2-Chloro-N-{3-[methyl(phenyl)sulfamoyl]phenyl}acetamide (CAS 380349-14-4)
- 3-((4-Chlorophenyl)sulfonyl)-1-(4-methoxyphenyl)propan-1-one (CAS 87015-44-9)
- 2-(2-(4-Chlorophenoxy)pyridin-3-yl)benzo[d]thiazole (CAS 337920-64-6)
- 1-Butyl-2,3,4,5,6,7-hexahydro-3-methyl-2,4,6-trioxo-1H-pyrrolo[2,3-d]pyrimidine-5-acetic acid (CAS 726153-21-5)
- N-(4-(4-Methoxyphenyl)thiazol-2-yl)-5,6-dihydro-1,4-dioxine-2-carboxamide (CAS 864937-65-5)
- 2,4-Dichloro-3-cyano-5-fluorobenzoic Acid (CAS 117528-58-2)
- 1-((4-Methoxyphenyl)sulfonyl)piperidin-4-amine (CAS 728015-65-4)
- 1-(2-((Benzyl(isopropyl)amino)methyl)pyrrolidin-1-yl)-2-chloroethanone (CAS 1353975-38-8)
- Methyl 2-amino-2-(5-bromo-2-fluorophenyl)acetate (CAS 1218158-22-5)
- N2,N2-Diallyl-2,5-pyridinediamine (CAS 1017171-94-6)
- 3-Amino-5-(3-fluorophenyl)-9-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one (CAS 1584632-49-4)
- 9,9'-(Butane-1,4-diyl)bis(9H-fluorene-9-carboxylic acid) (CAS 1881321-31-8)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
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