Ethyl 3-(bromomethyl)-4-chlorobenzoate CAS 335013-00-8
| CAS No. | 335013-00-8 |
| Molecular Formula | C10H10BrClO2 |
| Molecular Weight | 277.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 3-(bromomethyl)-4-chlorobenzoate.
CATO supplies Ethyl 3-(bromomethyl)-4-chlorobenzoate (CAS 335013-00-8), a certified reference material (molecular formula C10H10BrClO2, MW 277.54 g/mol) for analytical method development and quality control.
Structurally, Ethyl 3-(bromomethyl)-4-chlorobenzoate (C10H10BrClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 277.54 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10BrClO2 |
| Molecular Weight | 277.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
Related Ethyl Standards
- 8-(Bromomethyl)-6-chloro-3,4-dihydro-2h-benzo[b][1,4]dioxepine (CAS 1094419-62-1)
- 4-(Bromomethyl)-3-chlorobenzoic acid ethyl ester (CAS 133486-61-0)
- Ethyl 2-(bromomethyl)-4-chlorobenzoate (CAS 15365-28-3)
- 2-(Bromomethyl)-2-(4-chlorophenyl)-1,3-dioxolane (CAS 3418-24-4)
- 6-(Bromomethyl)tridecane (CAS 85531-03-9)
- 1-(Bromomethyl)-1-isopropoxy-4-isopropylcyclohexane (CAS 1247783-68-1)
- 1-(Bromomethyl)-1-(sec-butoxy)-4-ethylcyclohexane (CAS 1248354-55-3)
- 1-(Bromomethyl)-1-(tert-butoxy)-4-ethylcyclohexane (CAS 1248704-90-6)
Recommended Standards
- Ethyl 2-bromo-2-(3-chlorophenyl)acetate (CAS 41024-33-3)
- Ethyl 3-bromo-2-chloro-5-methylbenzoate (CAS 2121855-15-8)
- Ethyl 2-bromo-2-(2-chlorophenyl)acetate (CAS 2856-79-3)
- Ethyl 3-chloro-2-(bromomethyl)benzoate (CAS 56427-72-6)
- 3-(Benzylthio)-4-methyl-5-(1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl)-4H-1,2,4-triazole (CAS 956741-68-7)
- 1-(3-Methoxypropyl)-1h-indol-4-amine (CAS 1339472-15-9)
- 5-[(3-Formylphenoxy)methyl]-2-furoic acid (CAS 881041-10-7)
- 6-Amino-4-(aminomethyl)-5-(difluoromethyl)nicotinonitrile (CAS 1805269-44-6)
- 5-Sulfosalicylic Acid Dihydrate (CAS 5965-83-3)
- Ethyl 4-(4-chlorophenyl)-2-oxobutanoate (CAS 83402-92-0)
- 2,4-Diphenylisoxazol-5(2H)-one (CAS 17229-74-2)
- N,N,N-Trimethylpropan-1-aminium (bromide) (CAS 2650-50-2)
- 6-Fluoro-N-[2-(1H-indol-3-yl)ethyl]pyridin-2-amine (CAS 478047-29-9)
- Semaglutide (CAS CATO-C4X-2226105)
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