Thiophene-3,4-dicarbonyl dichloride CAS 33527-26-3
| CAS No. | 33527-26-3 |
| Molecular Formula | C6H2Cl2O2S |
| Molecular Weight | 209.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Thiophene-3,4-dicarbonyl dichloride (CAS 33527-26-3), a certified reference material (molecular formula C6H2Cl2O2S, MW 209.05 g/mol) for analytical method development and quality control.
Structurally, Thiophene-3,4-dicarbonyl dichloride (C6H2Cl2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 209.05 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Thiophene-3,4-dicarbonyl dichloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2Cl2O2S |
| Molecular Weight | 209.05 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1966 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related Thiophene Standards
- Thiophene-2,5-dicarbonyl dichloride (CAS 3857-36-1)
- 1-(Thiophene-2-carbonyl)piperidin-4-one (CAS 141945-71-3)
- 2-(Thiophene-2-carbonyl)cyclohexan-1-one (CAS 404858-18-0)
- 2-Methyl-1-(thiophene-2-carbonyl)piperazine (CAS 1240581-78-5)
- 1-(Thiophene-3-carbonyl)-1,4-diazepane (CAS 926247-21-4)
- Thiophene impurity 4 (CAS 200561-81-5)
- 4-Methyl-2-(thiophene-3-carbonyl)pentanenitrile (CAS 1247377-80-5)
- 1-(Thiophene-2-carbonyl)azetidine-3-carboxylic acid (CAS 1339416-02-2)
Recommended Standards
- 2,2,2-trifluoro-N-(2,2,2-trifluoroacetyl)acetamide 407-24-9 Bistrifluoroacetamide (CAS 407-24-9)
- Disodium Etidronate-d3 (methyl-d3) (CAS 358730-93-5)
- 4,6-Dichloro-N-(methyl-d3)pyridazine-3-carboxamide (CAS 1609393-89-6)
- 6-Butoxy-2-methylpyridine-3-boronic acid (CAS 2096339-72-7)
- Ethyl 2-((2,4-difluorophenyl)amino)-2-oxoacetate (CAS 333441-80-8)
- 1-(2-Amino-5-morpholinophenyl)ethan-1-one (CAS 98440-50-7)
- N-(2-Methyl-1,3-dioxoisoindolin-4-yl)-2-(phenylthio)acetamide (CAS 895485-73-1)
- 4-Bromo-1-ethynyl-2-fluorobenzene (CAS 302912-33-0)
- 7-fluoro-1H-indazole-4-carboxylic acid (CAS 1783619-00-0)
- 3-Methyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione hydrochloride (CAS 28937-15-7)
- 2-(5-(Trifluoromethyl)-1H-pyrazol-3-yl)pyridine (CAS 3974-71-8)
- Sodium orthosilicate (CAS 13472-30-5)
- alpha-Zearalenol (CAS 36455-72-8)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
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