(e)-2-(2-Chlorophenyl)ethene-1-sulfonyl chloride CAS 335281-13-5
| CAS No. | 335281-13-5 |
| Molecular Formula | C8H6Cl2O2S |
| Molecular Weight | 237.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(e)-2-(2-Chlorophenyl)ethene-1-sulfonyl chloride (CAS 335281-13-5), molecular formula C8H6Cl2O2S and molecular weight 237.10 g/mol, is a CATO reference standard with documented purity and traceability.
(e)-2-(2-Chlorophenyl)ethene-1-sulfonyl chloride (C8H6Cl2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (e)-2-(2-Chlorophenyl)ethene-1-sulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2O2S |
| Molecular Weight | 237.10 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 1 |
Related e Standards
- 2-(3-chlorophenyl)ethene-1-sulfonyl chloride (CAS 159800-73-4)
- 2-(2-Chlorophenyl)ethene-1-sulfonyl chloride (CAS 17811-58-4)
- (E)-2-(4-Chlorophenyl)ethylenesulfonyl chloride (CAS 52147-98-5)
- (4-Chlorophenyl)(cycloheptyl)methanone (CAS 1233011-42-1)
- 3-(3-Chlorophenyl)-1-cyclopropylpiperazine (CAS 1248907-81-4)
- 3-(2-Chlorophenyl)-1-cyclopropylpiperazine (CAS 1248907-94-9)
- 3-(4-Chlorophenyl)-1-cyclopropylpiperazine (CAS 1248908-14-6)
- (2-Chlorophenyl)(cycloheptyl)methanone (CAS 1443304-21-9)
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- (6-Bromonaphthalen-2-yl)hydrazine (CAS 752980-25-9)
- (4-Bromonaphthalen-1-yl)hydrazine (CAS 35158-78-2)
- [(2,6-dichlorophenyl)thio]acetic acid (CAS 21248-45-3)
- (2-Bromoquinolin-3-yl)methanamine (CAS 292077-58-8)
- Methyl 2-(1-(3-formyl-9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)-3-oxopiperazin-2-yl)acetate (CAS 1706667-11-9)
- Ethyl 2-(3-chloropropanamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate (CAS 314244-45-6)
- 2-(7-Chloro-1H-indol-3-yl)ethanamine hydrochloride (CAS 81868-13-5)
- 5-Ethyl-4H-1,2,4-triazole-3-carboxylic acid (CAS 107469-68-1)
- 1-Methyl-N-((1-methyl-1h-pyrrol-2-yl)methyl)pyrrolidin-3-amine (CAS 1247983-09-0)
- 7-Benzyl-1,4-dioxa-8-azaspiro[4.5]decane (CAS 193201-63-7)
- 5-(3-Chloropropyl)-3-phenyl-1,2,4-oxadiazole (CAS 91066-23-8)
- Diethyl 2-(2,4-difluorophenyl)malonate (CAS 137186-30-2)
- 2-(Cyclopentanesulfonyl)aniline (CAS 76697-51-3)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
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