Methyl 5-((2-chloro-5-(trifluoromethyl)phenyl)carbamoyl)-4-methyl-2-(2-methylbenzamido)thiophene-3-carboxylate CAS 335408-04-3
| CAS No. | 335408-04-3 |
| Molecular Formula | C23H18ClF3N2O4S |
| Molecular Weight | 510.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Methyl 5-((2-chloro-5-(trifluoromethyl)phenyl)carbamoyl)-4-methyl-2-(2-methylbenzamido)thiophene-3-carboxylate (CAS 335408-04-3), molecular formula C23H18ClF3N2O4S and molecular weight 510.91 g/mol, is a CATO reference standard with documented purity and traceability.
Methyl 5-((2-chloro-5-(trifluoromethyl)phenyl)carbamoyl)-4-methyl-2-(2-methylbenzamido)thiophene-3-carboxylate (C23H18ClF3N2O4S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H18ClF3N2O4S |
| Molecular Weight | 510.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- (3S,4S)-3-Hexyl-4-[(2S)-2-[[tris(1-methylethyl)silyl]oxy]tridecyl]-2-oxetanone (3S,4S)-3-Hexyl-4[(S)-2-(triisopropylsilyloxy)tridecyl]-2-oxetanone 1072902-84-1 (CAS 1072902-84-1)
- Calcipotriol Impurity 15 (CAS 104846-63-1)
- (S)-tert-Butyl-dimethyl-(4-methylene-3-(2-[7R-methyl-1R-(1R,4R,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene)-cyclohexyloxy)-silane (CAS 104846-62-0)
- 1,2-Bis(hexadecyloxy)ethane (CAS 17367-09-8)
- 4'-Cyano-biphenyl-4-acetic acid (CAS 144529-87-3)
- 7-methyl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1260639-77-7)
- N-Benzyl-N-ethyl-4-methylbenzamide (CAS 349091-12-9)
- 1,2,4-Triazolo[4,3-a]pyridine-7-carbonitrile (CAS 1019024-86-2)
- 1-(1-Cyclopropylethyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1153362-11-8)
- 2,4-Dichloro-5-(difluoromethyl)-3-nitropyridine (CAS 1806802-54-9)
- Loratadine Impurity 91 (CAS CATO-C4X-142691)
- (1,2,3,4-tetrahydroquinolin-5-yl)urea (CAS 1016712-93-8)
- (3-Chloro-5-(pyrrolidine-1-carbonyl)phenyl)boronic acid (CAS 1264616-21-8)
- Semaglutide Impurity 6 (CAS 62-57-7)
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